Evidence map›Paper›PMID 36916034›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

Therapeutic effect of

Laura Aguado, Ana Joya, Maider Garbizu, Sandra Plaza-García, Leyre Iglesias, María Isabel Hernández, María Ardaya, Naroa Mocha, Vanessa Gómez-Vallejo, Unai Cossio and 8 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Multimodal imaging of the role of hyperglycemia following experimental subarachnoid hemorrhage.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Laura AguadoAchucarro Basque Center for Neuroscience, Leioa, Spain.
Ana JoyaAchucarro Basque Center for Neuroscience, Leioa, Spain.
Maider GarbizuAchucarro Basque Center for Neuroscience, Leioa, Spain.
Sandra Plaza-GarcíaCIC biomaGUNE, Basque Research and Technology Alliance, San Sebastian, Spain.
Leyre IglesiasAchucarro Basque Center for Neuroscience, Leioa, Spain.
María Isabel HernándezAchucarro Basque Center for Neuroscience, Leioa, Spain.
María ArdayaAchucarro Basque Center for Neuroscience, Leioa, Spain.ORCID 0000-0002-0103-5649
Naroa MochaAchucarro Basque Center for Neuroscience, Leioa, Spain.
Vanessa Gómez-VallejoCIC biomaGUNE, Basque Research and Technology Alliance, San Sebastian, Spain.
Unai CossioCIC biomaGUNE, Basque Research and Technology Alliance, San Sebastian, Spain.
Makoto HiguchiNational Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.
Alfredo Rodríguez-AntigüedadDepartment of Neurology, Cruces University Hospital, Barakaldo, Spain.
Mari Mar FreijoNeurovascular Group, Biocruces Health Research Institute, Barakaldo, Spain.
María DomercqAchucarro Basque Center for Neuroscience, Leioa, Spain.
Carlos MatuteAchucarro Basque Center for Neuroscience, Leioa, Spain.ORCID 0000-0001-8672-711X
Pedro Ramos-CabrerCIC biomaGUNE, Basque Research and Technology Alliance, San Sebastian, Spain.
Jordi LlopCIC biomaGUNE, Basque Research and Technology Alliance, San Sebastian, Spain.
Abraham MartínAchucarro Basque Center for Neuroscience, Leioa, Spain.
CIC biomaGUNE · ESAchucarro Basque Center for Neuroscience · ESBioCruces Health research Institute · ESIkerbasque · ESUniversity of the Basque Country · ESHospital de Cruces · ESNational Institutes for Quantum Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinic acetylcholine α7 receptors (α7 nAChRs) have a well-known modulator effect in neuroinflammation. Yet, the therapeutical effect of α7 nAChRs activation after stroke has been scarcely evaluated to date. The role of α7 nAChRs activation with PHA 568487 on inflammation after brain ischemia was assessed with positron emission tomography (PET) using [

Indexed as

Brain IschemiaIschemic StrokeReceptors, Nicotinicalpha7 Nicotinic Acetylcholine ReceptorAnimalsAza CompoundsDioxinsInfarction, Middle Cerebral ArteryRatsalpha7 Nicotinic Acetylcholine ReceptorAza CompoundsDioxinsPHA-568487EReceptors, NicotinicCerebral ischemiametalloproteinasesMRIneuroinflammationPET

Identifiers

PMID36916034
PMCPMC10369150
OpenAlexW4324130174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.