Evidence map›Paper›PMID 36915779›Full record

ArticleAmerican journal of translational research2023

A modified pixel value ratio based on contralateral normal bone: a novel reliable indicator for distraction osteogenesis.

Qi Liu, Jieyu Liang, Ze Liu, Haibo Mei, Guanghui Zhu, Hongbin Guo, Min Wang, Yi Zhang

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Qi LiuDepartment of Orthopaedics, Xiangya Hospital, Central South University Changsha, Hunan, China.
Jieyu LiangDepartment of Orthopaedics, Xiangya Hospital, Central South University Changsha, Hunan, China.
Ze LiuDepartment of Orthopaedics, Xiangya Hospital, Central South University Changsha, Hunan, China.
Haibo MeiDepartment of Pediatric Orthopedics, Hunan Children's Hospital, Pediatric Academy of University of South China Changsha, Hunan, China.
Guanghui ZhuDepartment of Pediatric Orthopedics, Hunan Children's Hospital, Pediatric Academy of University of South China Changsha, Hunan, China.
Hongbin GuoDepartment of Orthopaedics, Xiangya Hospital, Central South University Changsha, Hunan, China.
Min WangDepartment of Endocrinology, Xiangya Hospital, Central South University Changsha, Hunan, China.
Yi ZhangDepartment of Orthopaedics, Xiangya Hospital, Central South University Changsha, Hunan, China.
Central South University · CNHunan Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe traditional pixel value ratio (tPVR) is subject to disuse osteopenia of the adjacent bone in distraction osteogenesis (DO). Therefore, a modified PVR (mPVR) based on the contralateral normal bone was developed and validated to address this issue.

methodsA total of 79 bone lengthening subjects were recruited in this retrospective study. The difference between the mPVR and tPVR of early callus was identified in the first three months after osteotomy. Moreover, we further investigated the relationship between mPVR and healing index (HI), lengthening index (LI) and external fixator index (EFI). Finally, the potential influencing factors for mPVR of the early callus were analyzed.

resultsThe mPVR was significantly lower than the tPVR in the first three months after osteotomy, and the difference gradually increased. Interestingly, the mPVR of the early callus in the first two months was negatively correlated with the HI, LI and EFI. Moreover, the age, lengthening site, total bilirubin and mean hemoglobin content were associated with the mPVR of early callus during DO.

conclusionThe mPVR based on contralateral normal bone is a novel reliable indicator for DO, which may be helpful for the clinical management of DO. However, the findings of this study need to be confirmed further by larger prospective research.

Indexed as

Bone lengtheningdistraction osteogenesisexternal fixatorIlizarov techniquemodified pixel value ratioplain radiography

Identifiers

PMID36915779
PMCPMC10006761
OpenAlexW4324129591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.