Evidence map›Paper›PMID 36915753›Full record

ArticleAmerican journal of translational research2023

Effects of letrozole combined with ethinylestradiol and cyproterone acetate tablets on serum sex hormones and lipid metabolism in patients with polycystic ovary syndrome.

Kena Lu, Na Li, Min Zhang, Jiajing Lin, Jiaquan Chen

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Kena LuDepartment of Gynecology, The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning 530023, Guangxi, China.
Na LiDepartment of Paediatrics, Yidu Central Hospital of Weifang Weifang 262500, Shandong, China.
Min ZhangDepartment of Joint Trauma Orthopaedics, Yidu Central Hospital of Weifang Weifang 262500, Shandong, China.
Jiajing LinDepartment of Gynecology, Liuzhou Worker's Hospital Liuzhou 530023, Guangxi, China.
Jiaquan ChenDepartment of Gynecology, The Second Affiliated Hospital of Mudanjiang Medical College Mudanjiang 157000, Heilongjiang, China.
Yidu Central Hospital of Weifang · CNLiuzhou Maternal and Child Health Hospital · CNMudanjiang Medical University · CNThe First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of letrozole combined with ethinylestradiol and cyproterone acetate tablets on serum sex hormones and lipid metabolism in patients with polycystic ovary syndrome (PCOS).

methodsClinical data of 152 PCOS patients in the First Affiliated Hospital of Guangxi University of Chinese Medicine from May 2019 to June 2021 were collected for a retrospective analysis. Among the patients, 73 treated with ethinylestradiol and cyproterone acetate tablets alone were seen as control group (CG), and the rest 79 with letrozole combined with ethinylestradiol and cyproterone acetate tablets were seen as observation group (OG). The treatment efficacy was observed, and the adverse reactions in the course of treatment were counted. The levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone (T), estrogen (E

resultsAfter the treatment, the total efficacy rate of the OG was higher than that of the CG (P<0.05); moreover, the levels of TC, TG, LDL, FSH, LH and T in OG were lower while HDL and E

conclusionLetrozole combined with ethinylestradiol and cyproterone acetate tablets can enhance the treatment efficiency of PCOS and improve serum sex hormones and lipid metabolism in PCOS patients.

Indexed as

ethinylestradiol and cyproterone acetate tabletsLetrozolelipid metabolismpolycystic ovary syndromesex hormone

Identifiers

PMID36915753
PMCPMC10006778
OpenAlexW4324129968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.