Evidence map›Paper›PMID 36915714›Full record

ReviewRegenerative biomaterials2023

Strategies of strengthening mechanical properties in the osteoinductive calcium phosphate bioceramics.

Qipeng Li, Cong Feng, Quanle Cao, Wei Wang, Zihan Ma, Yonghao Wu, Tinghan He, Yangtian Jing, Wenxuan Tan, Tongxiao Liao and 6 more

Full text readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Regenerative biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qipeng LiCollege of Chemical Engineering, Sichuan University, Chengdu 610065, China.
Cong FengNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Quanle CaoNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Wei WangCollege of Materials Science and Engineering, Sichuan University, Chengdu 610064, China.
Zihan MaCollege of Materials Science and Engineering, Sichuan University, Chengdu 610064, China.
Yonghao WuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Tinghan HeNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Yangtian JingCollege of Materials Science and Engineering, Sichuan University, Chengdu 610064, China.
Wenxuan TanCollege of Materials Science and Engineering, Sichuan University, Chengdu 610064, China.
Tongxiao LiaoCollege of Materials Science and Engineering, Sichuan University, Chengdu 610064, China.
Jie XingCollege of Materials Science and Engineering, Sichuan University, Chengdu 610064, China.
Xiangfeng LiNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Ye WangCollege of Chemical Engineering, Sichuan University, Chengdu 610065, China.
Yumei XiaoNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Xiangdong ZhuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.
Xingdong ZhangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University, Chengdu 610065, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium phosphate (CaP) bioceramics are widely applied in the bone repairing field attributing to their excellent biological properties, especially osteoinductivity. However, their applications in load-bearing or segmental bone defects are severely restricted by the poor mechanical properties. It is generally considered that it is challenging to improve mechanical and biological properties of CaP bioceramics simultaneously. Up to now, various strategies have been developed to enhance mechanical strengths of CaP ceramics, the achievements in recent researches need to be urgently summarized. In this review, the effective and current means of enhancing mechanical properties of CaP ceramics were comprehensively summarized from the perspectives of fine-grain strengthening, second phase strengthening, and sintering process optimization. What's more, the further improvement of mechanical properties for CaP ceramics was prospectively proposed including heat treatment and biomimetic. Therefore, this review put forward the direction about how to compatibly improve mechanical properties of CaP ceramics, which can provide data and ideas for expanding the range of their clinical applications.

Indexed as

CaP ceramicsenhancementmechanical propertyosteoinductivitystrategy

Identifiers

PMID36915714
PMCPMC10008083

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.