Evidence map›Paper›PMID 36915699›Full record

ArticleInternational journal of nanomedicine2023

Synthetic Antibacterial Quaternary Phosphorus Salts Promote Methicillin-Resistant

Liang-Wen Shi, Quan-Quan Zhuang, Tai-Qin Wang, Xian-Dong Jiang, Yue Liu, Jing-Wen Deng, Huan-Huan Sun, Yi Li, Hao-Hong Li, Ting-Bo Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Ultrastructural polymicrobialFuture microbiology · 2025
    Article
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Liang-Wen Shi *Department of Otorhinolaryngology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People's Republic of China.
Quan-Quan Zhuang *Department of Pharmacy, Affiliated Quanzhou First Hospital of Fujian Medical University, Quanzhou, Fujian, People's Republic of China.
Tai-Qin WangDepartment of Otorhinolaryngology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People's Republic of China.
Xian-Dong JiangDepartment of laboratory medicine, the School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Yue LiuCollege of Chemistry, Fuzhou University, Fuzhou, Fujian, People's Republic of China.
Jing-Wen DengDepartment of Otorhinolaryngology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People's Republic of China.
Huan-Huan SunDepartment of Otolaryngology, Changji Region Hospital of Traditional Chinese Medicine, Changji, Xinjiang, People's Republic of China.
Yi LiCollege of Chemistry, Fuzhou University, Fuzhou, Fujian, People's Republic of China.ORCID 0000-0001-9865-5141
Hao-Hong LiCollege of Chemistry, Fuzhou University, Fuzhou, Fujian, People's Republic of China.
Ting-Bo LiuFujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People's Republic of China.
Jian-Zhi LiuDepartment of Otorhinolaryngology, Fujian Medical University Union Hospital, Fuzhou, Fujian, People's Republic of China.
Fujian Medical University · CNFuzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Drug-resistant microbes pose a global health concern, requiring the urgent development of effective antibacterial agents and strategies in clinical practice. Therefore, there is an urgent need to explore novel antibacterial materials to effectively eliminate bacteria. The synthesis of quaternary phosphonium salt in haloargentate systems, wherein the phosphorus atom is represented in a cationic form, is a possible strategy for the development of antibacterial materials. Methods: Using (triphenyl)phosphonium-based quaternary phosphorus salts with different spacer lengths (n=2, 4, 6) as a template, we designed three kinds of quaternary phosphorus salts as effective antibacterial agents against drug-resistant bacteria. Results: The synthesized quaternary phosphorus salt of (1,4-DBTPP)Br Conclusion: The quaternary phosphorus salt (1,4-DBTPP)Br

Indexed as

Methicillin-Resistant Staphylococcus aureusAnimalsAnti-Bacterial AgentsMicrobial Sensitivity TestsPhosphorusRatsSaltsSodium ChlorideWound HealingAnti-Bacterial AgentsPhosphorusSaltsSodium Chlorideantibacterialbiocompatiblequaternary phosphorus saltsreactive oxygen specieswound infection therapy

Identifiers

PMID36915699
PMCPMC10007997
OpenAlexW4323360821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.