Evidence map›Paper›PMID 36915679›Full record

ArticleiScience2023

Bulk and mosaic deletions of

Xuying Zhang, Guanxi Xiao, Caroline Johnson, Yuheng Cai, Zachary K Horowitz, Christine Mennicke, Robert Coffey, Mansoor Haider, David Threadgill, Rebecca Eliscu and 3 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. NOTCH, ERK, and SHH signaling respectively control the fate determination of cortical glia and olfactory bulb interneurons.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Calcium and Neural Stem Cell Proliferation.International journal of molecular sciences · 2024
    Review
  8. ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Xuying ZhangDepartment of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA.
Guanxi XiaoDepartment of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA.
Caroline JohnsonDepartment of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA.
Yuheng CaiJoint Department of Biomedical Engineering, North Carolina State University and University of North Carolina at Chapel Hill, Raleigh, NC, USA.
Zachary K HorowitzDepartment of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA.
Christine MennickeDepartment of Mathematics, North Carolina State University, Raleigh, NC, USA.
Robert CoffeyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Mansoor HaiderDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
David ThreadgillInstitute for Genome Sciences and Society, Texas A&M University, College Station, TX, USA.
Rebecca EliscuDepartment of Neurological Surgery, University of California at San Francisco, San Francisco, CA, USA.
Michael C OldhamDepartment of Neurological Surgery, University of California at San Francisco, San Francisco, CA, USA.
Alon GreenbaumJoint Department of Biomedical Engineering, North Carolina State University and University of North Carolina at Chapel Hill, Raleigh, NC, USA.
H Troy GhashghaeiDepartment of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA.
North Carolina State University · USNeurological Surgery · USUniversity of North Carolina at Chapel Hill · USVanderbilt University Medical Center · USTexas A&M University · US

Funding

Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal CancerP50CA236733 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Robert J. Coffey · 2019 to 2026
$19.6M
Multiscale transcriptional architecture of the human brainR01MH123156 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OLDHAM, MICHAEL CLARK · 2020 to 2023
$2.4M
Decoding the molecular basis of cellular identity in the human brainR01MH113896 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OLDHAM, MICHAEL CLARK · 2018 to 2022
$2.0M
Mechanisms of cytokinesis and delamination in the cerebral corticesR01NS089795 · NINDS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI GHASHGHAEI, HOOMAN TROY · 2014 to 2018
$1.7M
Role of ependyma in forebrain homeostasisR01NS098370 · NINDS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI GHASHGHAEI, HOOMAN TROY · 2016 to 2020
$1.6M
High Throughput Clonal Analyses of Gliogenesis in Neocortical and Paleocortical areas of the Mouse BrainR21NS129093 · NINDS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI GHASHGHAEI, HOOMAN TROY, GREENBAUM, ALON · 2022 to 2022
$412k
NCI NIH HHS P50 CA236733NIMH NIH HHS R01 MH113896NIMH NIH HHS R01 MH123156NINDS NIH HHS R01 NS089795NINDS NIH HHS R01 NS098370NINDS NIH HHS R21 NS129093
6 · The paper itself

Abstract

The epidermal growth factor receptor (EGFR) plays a role in cell proliferation and differentiation during healthy development and tumor growth; however, its requirement for brain development remains unclear. Here we used a conditional mouse allele for

Indexed as

Developmental neuroscienceNeuroscienceOmicsTranscriptomics

Identifiers

PMID36915679
PMCPMC10006693
OpenAlexW4321378847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.