Evidence map›Paper›PMID 36915422›Full record

ArticleInternational journal of general medicine2023

Poor Seizure Control Among Children Attending a Tertiary Hospital in South Western Uganda - A Retrospective Study.

Jane Namusisi, Stella Kyoyagala, Josephine Nantongo, Mike Kyewalyanga, Stephen Sabiiti, Angelique Murorunkwere, Josephine Nambi Najjuma, Jane Nakibuuka, Mark Kaddumukasa, Martha Sajatovic and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jane NamusisiDepartment of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda.ORCID 0000-0003-4803-8369
Stella KyoyagalaDepartment of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda.
Josephine NantongoDepartment of Pediatrics and Child Health, Mbarara Regional Referral Hospital (MRRH), Mbarara, Uganda.
Mike KyewalyangaDepartment of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda.
Stephen SabiitiDepartment of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda.
Angelique MurorunkwereDepartment of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda.
Josephine Nambi NajjumaDepartment of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda.
Jane NakibuukaDepartment of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Mark KaddumukasaDepartment of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0001-7390-7330
Martha SajatovicNeurological and Behavioral Outcomes Center, University Hospital Case Medical Center, Case Western Reserve University, Cleveland, OH, USA.
Peter KalubiDepartment of Pediatrics and Child Health, Mbarara University of Science and Technology (MUST), Mbarara, Uganda.ORCID 0000-0001-5544-9524
Mbarara University of Science and Technology · UGMakerere University · UGCase Western Reserve University · USMbarara National Referral Hospital · UG

Funding

A Targeted Self-Management Intervention for Reducing Stroke Risk Factors in High Risk UgandansR01NS118544 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI KATABIRA, ELLY T, SAJATOVIC, MARTHA X · 2020 to 2025
$3.0M
NINDS NIH HHS R01 NS118544
6 · The paper itself

Abstract

Background: Seizure control among children with epilepsy (CWE) receiving anti-seizure medications (ASMs) remains a challenge in low-resource settings. Uncontrolled seizures are significantly associated with increased morbidity and mortality among CWE. This negatively impacts their quality of life and increases stigma. Aim: This study determined seizure control status and described the factors associated among CWE receiving ASMs at Mbarara Regional Referral Hospital (MRRH). Methods: In a retrospective chart review study, socio-demographic and clinical data were obtained from 112 medical records. CWE receiving ASMs for at least six months and regularly attending the clinic were included in the study. Physical or telephone interviews were conducted with the immediate caregivers of the CWE to establish the current seizure control status of the participants. Results: A total of 112 participants were enrolled. Of these, three-quarters had generalized onset seizures, 23% had focal onset seizures, while 2% had unknown onset motor seizures. About 60.4% of the study participants had poor seizure control. Having a comorbidity ( Conclusion: Seizure control among CWE receiving ASMs at MRRH remains poor. Efforts geared to addressing seizure control and optimizing drugs are needed, especially among children with comorbidities, those with history of birth asphyxia, and adolescents.

Indexed as

anti-seizure medicationschildrenepilepsyseizure controlUganda

Identifiers

PMID36915422
PMCPMC10007866
OpenAlexW4323365119

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.