Evidence map›Paper›PMID 36915367›Full record

ArticleKidney medicine2023

A Half-Century Dialysis Survivor: Clinical and Autopsy Findings.

Noto Okubo, Tatsuya Suwabe, Yuki Oba, Daisuke Ikuma, Hiroki Mizuno, Akinari Sekine, Eiko Hasegawa, Masayuki Yamanouchi, Junichi Hoshino, Izuru Kitajima and 6 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Kidney medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Noto OkuboNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Tatsuya SuwabeNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Yuki ObaNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Daisuke IkumaNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Hiroki MizunoNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Akinari SekineNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Eiko HasegawaNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Masayuki YamanouchiNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Junichi HoshinoNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Izuru KitajimaDepartment of Orthopedic Surgery, Toranomon Hospital, Tokyo, Japan.
Masanori ShibaDepartment of Cardiovascular Medicine, Toranomon Hospital, Tokyo, Japan.
Koki UrugaDepartment of Pathology, Toranomon Hospital, Tokyo, Japan.
Fuji TakeshiDepartment of Pathology, Toranomon Hospital, Tokyo, Japan.
Kenichi OhashiDepartment of Pathology, Toranomon Hospital, Tokyo, Japan.
Naoki SawaNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Yoshifumi UbaraNephrology Center and Okinawa Memorial Institute for Medical Research, Toranomon Hospital, Kajigaya, Japan.
Toranomon Hospital · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man in his 20s initiated intermittent peritoneal dialysis in the late 1960s. He subsequently transitioned to hemodialysis and survived for more than 50 years, spanning low-flux and high-flux hemodialysis eras. He underwent surgery for cervical and lumbar spinal canal stenosis after 30 and 35 years, respectively, and both surgeries revealed similar degrees of severe amyloid deposition. At autopsy, significant improvement was seen in lumbar amyloid deposition. During the previous 25 years, serum β2 microglobulin levels had decreased from 40 mg/L and been maintained at 20 mg/L. This case indicates that advances in dialysis therapy aimed at lowering β2 microglobulin concentrations have reduced highly deposited amyloid.

Indexed as

Dialysis-related amyloidosishemodialysisintermittent peritoneal dialysis

Identifiers

PMID36915367
PMCPMC10006697
OpenAlexW4319441668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.