ArticleBMC cardiovascular disorders2023
Interaction effects between sleep disorders and depression on heart failure.
Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Prevalence and determinants of insomnia in patients with chronic heart failure: a cross-sectional survey in Jiaxing, China.Frontiers in cardiovascular medicine · 2026Article
- Network analysis of sleep quality-anxiety-depressive symptoms among patients with chronic heart failure.Frontiers in psychiatry · 2026Article
- Poor Sleep Pattern Might Increase the Prevalence of Abdominal Aortic Calcification in US Adults: Data from the NHANES (2013-2014).Vascular health and risk management · 2025Article
- Interaction effects between sleep-related disorders and depression on hypertension among adults: a cross-sectional study.BMC psychiatry · 2024Article
- The interaction effects between depression and sleep status on asthma: a national cross-sectional study.Frontiers in psychiatry · 2024Article
- The mediating role of sleep disturbance in the relationship between depression and cardiovascular disease.Frontiers in psychiatry · 2024Article
- The Combined Effect Between Sleep Disorders and Depression Symptoms on Chronic Low Back Pain: A Cross-Sectional Study of NHANES.Journal of pain research · 2024Article
- Association between the healthy eating index 2020 and heart failure among the U.S. middle-aged and older adults from NHANES 2005-2020: a cross-sectional study.Frontiers in nutrition · 2024Article
- The relationship between preserved ratio impaired spirometry and mortality in the myocardial infarction survivors: a population-based cohort study.BMC cardiovascular disorders · 2023Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSleep disorders and depression were recognized as independent risk factors for heart failure, whether their interaction effects also correlated with the risk of heart failure remains elusive. This study was to explore the interaction effects between sleep disorders and depression on the risk of heart failure.
methodsThis was a cross-sectional study that included data from 39,636 participants in the National Health and Nutritional Examination Survey (NHANES) database. Poisson regression model was applied to evaluate the associations of depression or sleep disorders with heart failure. The relative excess risk of interaction (RERI), attributable proportion of interaction (API) and synergy index (SI) were used to measure whether the interaction effects between depression and sleep disorders on heart failure was statistically significant.
resultsThe risk of heart failure was increased in people with sleep disorders [risk ratio (RR) = 1.92, 95% confidence interval (CI): 1.68-2.19) after adjusting for confounders including age, gender, body mass index (BMI), race, marital status, education level, annual family income, drinking history, smoking history, diabetes, hypertension and stroke. The risk of heart failure was elevated in patients with depression after adjusting for confounders (RR = 1.96, 95%CI: 1.65-2.33). Patients with depression and sleep disorders were associated with increased risk of heart failure after adjusting for confounders (RR = 2.76, 95%CI: 2.23-3.42). The CIs of interactive indexes RERI was -0.42 (95%CI: -1.23-0.39), and API was -0.15 (95%CI: -0.46-0.16), which included 0. The CI of interactive indexes SI was 0.81 (95%CI: 0.54-1.21), which contained 1.
conclusionDepression and sleep disorders were independent risk factors for heart failure but the interaction effects between depression and sleep disorders on the occurrence of heart failure were not statistically different.
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