Evidence map›Paper›PMID 36914983›Full record

ArticleJournal of the American Geriatrics Society2023

Frequency and implications of coexistent manifestations of serious illness in older adults with dementia.

Stephanie Nothelle, Evan Bollens-Lund, Kenneth E Covinsky, Amy Kelley

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephanie NothelleCenter for Transformative Geriatrics Research, Division of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-3908-286X
Evan Bollens-LundBrookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-8402-7635
Kenneth E CovinskyDivision of Geriatrics, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Amy KelleyBrookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-6345-9834

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2013 to 2026
$19.9M
Unnecessary and Harmful Medication Use in Older Adults with DementiaP01AG066605 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MELISSA Diane ALDRIDGE · 2020 to 2026
$17.7M
Remote Data Enclave Core (RDEC)P30AG066587 · NIA · JOHNS HOPKINS UNIVERSITY · PI DANIEL E POLSKY, Jennifer L. Wolff · 2020 to 2026
$6.7M
Primary care based collaborative approach to care management for older adults with dementiaK23AG072037 · NIA · JOHNS HOPKINS UNIVERSITY · PI NOTHELLE, STEPHANIE · 2021 to 2025
$946k
Midcareer Investigator Award for Patient-Oriented Research in Dementia and Serious IllnessK24AG062785 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KELLEY, AMY STEVES · 2019 to 2022
$581k
Characterization and effect of co-existence of care management programs for high need, high cost older adultsR03AG060170 · NIA · JOHNS HOPKINS UNIVERSITY · PI NOTHELLE, STEPHANIE · 2018 to 2019
$246k
NIA NIH HHS K23 AG072037NIA NIH HHS K23AG072037NIA NIH HHS K24 AG062785NIA NIH HHS K24AG062785NIA NIH HHS L30 AG064736NIA NIH HHS P01 AG066605NIA NIH HHS P01AG066605NIA NIH HHS P30 AG044281NIA NIH HHS P30AG044281NIA NIH HHS P30 AG066587NIA NIH HHS R03 AG060170
6 · The paper itself

Abstract

backgroundIn older adults, serious illness comprises three manifestations: dementia, activity of daily living (ADL) impairment, and other advanced medical conditions (AMC; e.g., end-stage renal disease). Little is known about how dementia and other manifestations of serious illness co-occur. We aim to describe the prevalence of persons with dementia (PWD) who are living with additional manifestations of serious illness, and the implications on healthcare utilization, Medicare costs, caregiving hours and out-of-pocket expenses.

methodsIn this cross-sectional study, we use data from the 2016 Health and Retirement Study (HRS) linked to Medicare fee-for-service claims. We limited inclusion to adults >65 years. Dementia was determined using validated methodology that incorporates functional and cognitive test scores from HRS. We classified PWD as having dementia alone, dementia and an AMC (irrespective of ADL impairment) or dementia and ADL impairment (without an AMC). Healthcare utilization and Medicare costs were measured in claims, caregiving hours and out-of-pocket expenses were self-reported.

resultsMost PWD (67%) met criteria for another manifestation of serious illness (24% advanced medical condition, 44% ADL impairment). PWD and an AMC had the highest proportion of hospital use and the highest median total Medicare costs ($17,900 vs. $8962 dementia + ADL impairment vs. $4376 dementia alone). Mean total hours of caregiving per month were similar for PWD and an AMC and PWD and ADL impairment (142.9 and 141.9 h, respectively), while mean hours were much lower for PWD alone (47.7 h). Median out-of-pocket costs were highest for PWD and ADL impairment ($13,261) followed by PWD and an AMC ($10,837) and PWD alone ($7017).

conclusionsPWD commonly face another manifestation of serious illness. Dementia and ADL impairment was associated with the highest costs for PWD and families while dementia and an AMC was associated with the highest costs for Medicare.

Indexed as

DementiaActivities of Daily LivingAgedCaregiversCosts and Cost AnalysisCross-Sectional StudiesHumansMedicarePatient Acceptance of Health CareUnited Statescaregivingcosts of caredementiaserious illness

Identifiers

PMID36914983
PMCPMC10363196

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.