Evidence map›Paper›PMID 36914821›Full record

ArticleScientific reports2023

Evaluating the use of large language model in identifying top research questions in gastroenterology.

Adi Lahat, Eyal Shachar, Benjamin Avidan, Zina Shatz, Benjamin S Glicksberg, Eyal Klang

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Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Large Language Models in Gastroenterology: Systematic Review.Journal of medical Internet research · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. ChatGPT in precision medicine.APL bioengineering · 2026
    Review
  8. Article
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  10. Article
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  16. Review
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  20. Exploring the benefits and challenges of AI-driven large language models in gastroenterology: Think out of the box.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adi LahatDepartment of Gastroenterology, Chaim Sheba Medical Center, Affiliated to Tel Aviv University, Tel Aviv, Israel. zokadi@gmail.com.
Eyal ShacharDepartment of Gastroenterology, Chaim Sheba Medical Center, Affiliated to Tel Aviv University, Tel Aviv, Israel.
Benjamin AvidanDepartment of Gastroenterology, Chaim Sheba Medical Center, Affiliated to Tel Aviv University, Tel Aviv, Israel.
Zina ShatzDepartment of Gastroenterology, Chaim Sheba Medical Center, Affiliated to Tel Aviv University, Tel Aviv, Israel.
Benjamin S GlicksbergHasso Plattner Institute for Digital Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Eyal KlangThe Sami Sagol AI Hub, ARC Innovation Center, Chaim Sheba Medical Center, Affiliated to Tel-Aviv University, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of gastroenterology (GI) is constantly evolving. It is essential to pinpoint the most pressing and important research questions. To evaluate the potential of chatGPT for identifying research priorities in GI and provide a starting point for further investigation. We queried chatGPT on four key topics in GI: inflammatory bowel disease, microbiome, Artificial Intelligence in GI, and advanced endoscopy in GI. A panel of experienced gastroenterologists separately reviewed and rated the generated research questions on a scale of 1-5, with 5 being the most important and relevant to current research in GI. chatGPT generated relevant and clear research questions. Yet, the questions were not considered original by the panel of gastroenterologists. On average, the questions were rated 3.6 ± 1.4, with inter-rater reliability ranging from 0.80 to 0.98 (p < 0.001). The mean grades for relevance, clarity, specificity, and originality were 4.9 ± 0.1, 4.6 ± 0.4, 3.1 ± 0.2, 1.5 ± 0.4, respectively. Our study suggests that Large Language Models (LLMs) may be a useful tool for identifying research priorities in the field of GI, but more work is needed to improve the novelty of the generated research questions.

Indexed as

GastroenterologistsGastroenterologyInflammatory Bowel DiseasesArtificial IntelligenceHumansReproducibility of Results

Identifiers

PMID36914821
PMCPMC10011374

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.