Evidence map›Paper›PMID 36914799›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Social disadvantage during pregnancy: effects on gestational age and birthweight.

Joan L Luby, Sarah K England, Deanna M Barch, Barbara B Warner, Cynthia Rogers, Christopher D Smyser, Regina Triplett, Jyoti Arora, Tara A Smyser, George M Slavich and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Prenatal Adversity and Neonatal Brain Connectivity Relate to Emerging Executive Function at Age 2 Years.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  7. Article
  8. Stress-induced developmental plasticity and spontaneous preterm birth: A justice-oriented eco-evo-devo review.European journal of obstetrics & gynecology and reproductive biology: X · 2025
    Review
  9. Healthcare (Basel, Switzerland) · 2025
    Review
  10. Structure-function coupling in the first month of life: Associations with age and attention.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Prenatal social disadvantage is associated with alterations in functional networks at birth.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Joan L Luby *Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. lubyj@wustl.edu.ORCID 0000-0001-5352-1721
Sarah K England *Department of Obstetrics and Gynecology, Center for Reproductive Health Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Deanna M BarchDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
Barbara B WarnerDepartment of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-9910-4461
Cynthia RogersDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-6251-8436
Christopher D SmyserDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-4716-5190
Regina TriplettDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-0595-0801
Jyoti AroraDivision of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-9957-4922
Tara A SmyserDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-2977-8214
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA.ORCID 0000-0001-5710-3818
Peinan ZhaoDepartment of Obstetrics and Gynecology, Center for Reproductive Health Sciences, Washington University School of Medicine, St. Louis, MO, USA.
Molly StoutDepartment of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
Erik HerzogDepartment of Biology, Washington University in St. Louis, St. Louis, MO, USA.ORCID 0000-0001-7209-5174
J Philip MillerDivision of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-4568-6846
Washington University in St. Louis · USUniversity of California, Los Angeles · USUniversity of Michigan · US

Funding

Early Life Adversity, Biological Embedding, and Risk for Developmental Precursors of Mental DisordersR01MH113883 · NIMH · WASHINGTON UNIVERSITY · PI JOAN L. LUBY, Christopher Daniel Smyser · 2018 to 2026
$20.6M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JOSEPH D DOUGHERTY, Natasha Marrus · 2020 to 2026
$15.5M
NICHD NIH HHS P50 HD103525NIMH NIH HHS R01 MH113883
6 · The paper itself

Abstract

objectiveWhether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide. STUDY

designMeasures of social disadvantage and psychological factors, and medical/reproductive and nutritional health status in pregnant women were obtained at each trimester. Using Structural Equation Modeling (SEM), we investigated the relationship of forms of adversity to each other and to infant gestational age, and birthweight.

resultsAmong 399 singletons, Social Disadvantage significantly predicted gestational age (p = 0.003), and residual birthweight (p = 0.006). There was a 0.4 week decrease in gestational age and a 3% decrease in birthweight for each standard deviation increase in Social Disadvantage.

conclusionSignificant negative effects of social adversity on the developing fetus were found. Notably, these effects emerged despite good prenatal care and after accounting for maternal age and medical reproductive risk factors.

Indexed as

Infant, Low Birth WeightPrenatal CareBirth WeightFemaleGestational AgeHumansInfantInfant, NewbornMaternal AgePregnancy

Identifiers

PMID36914799
PMCPMC10079545
OpenAlexW4324129677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.