Evidence map›Paper›PMID 36914792›Full record

ArticleNature chemistry2023

Connecting the geometric and electronic structures of the nitrogenase iron-molybdenum cofactor through site-selective

Edward D Badding, Suppachai Srisantitham, Dmitriy A Lukoyanov, Brian M Hoffman, Daniel L M Suess

Abstract read
In one paragraph

Article in Nature chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Synthetic models of the nitrogenase FeMo cofactor.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. NifEN: a versatile player in nitrogenase assembly, catalysis and evolution.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Review
  7. Article
  8. Molecular sorting of nitrogenase catalytic cofactors.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Cluster-selectiveChemical science · 2023
    Article
  12. Article
  13. Journal of the American Chemical Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Edward D BaddingDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-6551-5185
Suppachai SrisantithamDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-9649-6156
Dmitriy A LukoyanovDepartment of Chemistry, Northwestern University, Evanston, IL, USA.
Brian M HoffmanDepartment of Chemistry, Northwestern University, Evanston, IL, USA.ORCID http://orcid.org/0000-0002-3100-0746
Daniel L M SuessDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA. suess@mit.edu.ORCID http://orcid.org/0000-0002-0916-1973

Funding

TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI YAFFE, MICHAEL B · 1985 to 2020
$25.6M
Coboglobins-Cobalt-Substituted Hemoglobins and MyoglobinR01GM111097 · NIGMS · NORTHWESTERN UNIVERSITY · PI HOFFMAN, BRIAN M · 2014 to 2025
$6.7M
Chemical Approaches to Studying the Mechanisms and Biophysical Properties of Complex MetallocofactorsR01GM145787 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SUESS, DANIEL LEIF MIGDOW · 2022 to 2024
$1.1M
NIEHS NIH HHS P30 ES002109NIGMS NIH HHS R01 GM111097NIGMS NIH HHS R01 GM145787
6 · The paper itself

Abstract

Understanding the chemical bonding in the catalytic cofactor of the Mo nitrogenase (FeMo-co) is foundational for building a mechanistic picture of biological nitrogen fixation. A persistent obstacle towards this goal has been that the

Indexed as

MolybdoferredoxinNitrogenaseCatalysisElectron Spin Resonance SpectroscopyOxidation-ReductionMolybdoferredoxinNitrogenase

Identifiers

PMID36914792
PMCPMC10710871

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.