Evidence map›Paper›PMID 36914719›Full record

ArticleScientific reports2023

Stress native T1 and native T2 mapping compared to myocardial perfusion reserve in long-term follow-up of severe Covid-19.

Jannike Nickander, Rebecka Steffen Johansson, Klara Lodin, Anton Wahrby, Daniel Loewenstein, Judith Bruchfeld, Michael Runold, Hui Xue, Peter Kellman, Henrik Engblom

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In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Jannike NickanderDepartment of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. jannike.nickander@ki.se.
Rebecka Steffen JohanssonDepartment of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Klara LodinDepartment of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Anton WahrbyDepartment of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Daniel LoewensteinDepartment of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Judith BruchfeldDivision of Infectious Diseases, Department of Medicine Solna, Karolinska Institutet, Solna, Sweden.
Michael RunoldDepartment of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.
Hui XueNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Peter KellmanNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Henrik EngblomDepartment of Clinical Physiology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SENational Heart Lung and Blood Institute · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe Covid-19 may cause a cascade of cardiovascular complications beyond viral pneumonia. The severe inflammation may affect the microcirculation which can be assessed by cardiovascular magnetic resonance (CMR) imaging using quantitative perfusion mapping and calculation of myocardial perfusion reserve (MPR). Furthermore, native T1 and T2 mapping have previously been shown to identify changes in myocardial perfusion by the change in native T1 and T2 during adenosine stress. However, the relationship between native T1, native T2, ΔT1 and ΔT2 with myocardial perfusion and MPR during long-term follow-up in severe Covid-19 is currently unknown. Therefore, patients with severe Covid-19 (n = 37, median age 57 years, 24% females) underwent 1.5 T CMR median 292 days following discharge. Quantitative myocardial perfusion (ml/min/g), and native T1 and T2 maps were acquired during adenosine stress, and rest, respectively. Both native T1 (R

Indexed as

COVID-19AdenosineCoronary CirculationFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMaleMiddle AgedPredictive Value of TestsAdenosine

Identifiers

PMID36914719
PMCPMC10010213
OpenAlexW4324129412

What OpenQuestion holds

Textfull text, public
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.