Evidence map›Paper›PMID 36914660›Full record

ArticleScientific reports2023

Compensatory gene expression potentially rescues impaired brain development in Kit mutant mice.

Ryuhei Minei, Hitomi Aoki, Atsushi Ogura, Takahiro Kunisada

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Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryuhei MineiDepartment of Bio-Science, Nagahama Institute of Bio-Science and Technology, Shiga, Japan.
Hitomi AokiDepartment of Tissue and Organ Development, Regeneration, and Advanced Medical Science, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
Atsushi OguraDepartment of Bio-Science, Nagahama Institute of Bio-Science and Technology, Shiga, Japan.
Takahiro KunisadaDepartment of Tissue and Organ Development, Regeneration, and Advanced Medical Science, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan. tkunisad@gifu-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While loss-of-function mutations in the murine dominant white spotting/Kit (W) locus affect a diverse array of cell lineages and organs, the brain, organ with the highest expression show the least number of defective phenotypes. We performed transcriptome analysis of the brains of Kit

Indexed as

BrainProto-Oncogene Proteins c-kitAnimalsGene ExpressionMiceMice, Mutant StrainsMutationPhenotypeProto-Oncogene Proteins c-kit

Identifiers

PMID36914660
PMCPMC10011532

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.