Evidence map›Paper›PMID 36914406›Full record

ArticleRespirology (Carlton, Vic.)2023

Sputum periostin is a biomarker of type 2 inflammation but not airway dysfunction in asthma.

Taha Al-Shaikhly, Ryan C Murphy, Ying Lai, Charles W Frevert, Jason S Debley, Steven F Ziegler, Kit Wong, Guiquan Jia, Cecile T J Holweg, Michael C Peters and 1 more

Open access · bronzeAbstract readLetter
In one paragraph

Article in Respirology (Carlton, Vic.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. The Past, the Present, and the Future of Periostin in Allergy.Allergy, asthma & immunology research · 2026
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Taha Al-ShaikhlyDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-1251-8937
Ryan C MurphyCenter for Lung Biology, University of Washington, Seattle, Washington, USA.ORCID 0000-0003-0094-0003
Ying LaiCenter for Lung Biology, University of Washington, Seattle, Washington, USA.
Charles W FrevertCenter for Lung Biology, University of Washington, Seattle, Washington, USA.
Jason S DebleyDepartment of Pediatrics, Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.
Steven F ZieglerImmunology Program, Benaroya Research Institute, Seattle, Washington, USA.
Kit WongGenentech, South San Francisco, California, USA.
Guiquan JiaGenentech, South San Francisco, California, USA.
Cecile T J HolwegGenentech, South San Francisco, California, USA.
Michael C PetersDepartment of Medicine, Division of Pulmonary and Critical Care, University of California San Francisco, San Francisco, California, USA.
Teal S HallstrandCenter for Lung Biology, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-5059-6872
University of Washington · USMercedes-Benz Research and Development North America (United States) · USSeattle Children's Hospital · USUniversity of California, San Francisco · US

Funding

Regulation of the Innate Immune Response by the Epithelium in AsthmaU19AI125378 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI ZIEGLER, STEVEN F · 2016 to 2020
$9.2M
The Bioinformatics and Data Management Core (BDMC)U19AI175089 · NIAID · UNIVERSITY OF WASHINGTON · PI JASON S DEBLEY, Teal S Hallstrand · 2023 to 2026
$7.8M
Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodelingR01AI163160 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI JASON S DEBLEY · 2022 to 2026
$4.3M
Origin and Function of Intra-epithelial Mast Cells in AsthmaR01HL153979 · NHLBI · UNIVERSITY OF WASHINGTON · PI HALLSTRAND, TEAL S · 2021 to 2024
$2.9M
Immunopathology of Indirect Airway Hyperresponsiveness in AsthmaK24AI130263 · NIAID · UNIVERSITY OF WASHINGTON · PI Teal S Hallstrand · 2017 to 2026
$1.3M
Impact of Heterogeneous Airway Epithelial ACE2 Expression and Interferon Responses on SARS-CoV2 Infectivity and ReplicationK24AI150991 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI DEBLEY, JASON S · 2020 to 2024
$1.2M
NHLBI NIH HHS R01 HL153979NIAID NIH HHS K24 AI130263NIAID NIH HHS K24 AI150991NIAID NIH HHS R01 AI163160NIAID NIH HHS U19 AI125378NIAID NIH HHS U19 AI175089NIH HHS U19AI125378
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaSputumBiomarkersEosinophilsHumansInflammationBiomarkersairway hyperresponsivenessasthmaIL-13IL-4IL-5periostintype-2

Identifiers

PMID36914406
PMCPMC10257949
OpenAlexW4324025824

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.