Evidence map›Paper›PMID 36914265›Full record

ArticleLife science alliance2023

The ERK activator, BCI, inhibits ciliogenesis and causes defects in motor behavior, ciliary gating, and cytoskeletal rearrangement.

Larissa L Dougherty, Soumita Dutta, Prachee Avasthi

Open access · goldFull text read
In one paragraph

Article in Life science alliance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Open isthmus and lambda sign of early Joubert syndrome: elucidating development of molar tooth sign.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Larissa L DoughertyBiochemistry and Cell Biology Department, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.ORCID https://orcid.org/0000-0002-7198-6722
Soumita DuttaAnatomy and Cell Biology Department, University of Kansas Medical Center, Kansas City, KS, USA.ORCID https://orcid.org/0000-0002-9677-7724
Prachee AvasthiBiochemistry and Cell Biology Department, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA prachee.avasthi@dartmouth.edu.ORCID https://orcid.org/0000-0002-1688-722X
Dartmouth College · USUniversity of Kansas Medical Center · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2016 to 2025
$25.9M
CYTOSKELETAL AND SIGNALING MECHANISMS REGULATING CILIARY TRAFFICR35GM128702 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI AVASTHI, PRACHEE · 2018 to 2021
$1.6M
NCI NIH HHS P30 CA023108NIGMS NIH HHS P20 GM113132NIGMS NIH HHS R35 GM128702
6 · The paper itself

Abstract

MAPK pathways are well-known regulators of the cell cycle, but they have also been found to control ciliary length in a wide variety of organisms and cell types from

Indexed as

Brain-Computer InterfacesAnimalsHumansMammalsMitogen-Activated Protein KinasesMitogen-Activated Protein Kinases

Identifiers

PMID36914265
PMCPMC10011610
OpenAlexW4324028277

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read13
measurements read105
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.