Evidence map›Paper›PMID 36914145›Full record

ArticlePhytochemistry2023

Bioactive and unusual steroids from Penicillium fungi.

Charmaine A Lindsay, A Douglas Kinghorn, Harinantenaina L Rakotondraibe

Open access · greenAbstract read
In one paragraph

Article in Phytochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Charmaine A LindsayDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
A Douglas KinghornDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.
Harinantenaina L RakotondraibeDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA. Electronic address: rakotondraibe.1@osu.edu.
The Ohio State University · US

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI JIMMY ORJALA · 2007 to 2026
$27.2M
NCI NIH HHS P01 CA125066
6 · The paper itself

Abstract

Penicillium fungi are represented by various species and can be found worldwide and thrive in a range of environments, such as in the soil, air, and indoors, and in marine environments, as well as food products. Chemical investigation of species of this genus has led to the discovery of compounds from several structural classes with varied bioactivities. As an example, this genus has been a source of bioactive and structurally unusual steroids. The scope of this short review is to cover specialized metabolites of the steroid class and the cytotoxic, antimicrobial, anti-inflammatory as well as phytotoxic activities of these compounds. Other steroids that possess unusual structures, with significant bioactivity yet to determined, will also be discussed to further demonstrate the structural diversity of this compound class from Penicillium fungi, and hopefully inspire the further exploration of such compounds to uncover their activity.

Indexed as

Anti-Infective AgentsAntineoplastic AgentsPenicilliumFungiSteroidsAnti-Infective AgentsAntineoplastic AgentsSteroidsAntibacterialAntifungalAnti-inflammatoryC(25) steroidCytotoxicityPenicilliumSteroids

Identifiers

PMID36914145
PMCPMC10077519
OpenAlexW4323922921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.