ArticleThe American journal of tropical medicine and hygiene2023
Detection of Sporadic Outbreaks of Rift Valley Fever in Uganda through the National Viral Hemorrhagic Fever Surveillance System, 2017-2020.
Article in The American journal of tropical medicine and hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Viral and host determinants of arboviral disease severity in African populations: A systematic review with meta-analysis.PLoS neglected tropical diseases · 2026Pooled it
- Seroprevalence of Rift Valley fever virus and factors associated with exposure in south-central Uganda.BMC infectious diseases · 2026Article
- Understanding the Rift Valley fever exposure risk: A comparative perspective from a multi-country study in East and Central Africa, 2021-24.PLoS neglected tropical diseases · 2026Article
- A Cross-Sectional Study of Rift Valley Fever Exposure in Humans and Livestock in Southwestern Uganda Using a One Health Approach: Evidence of Elevated Seroprevalence Outside Recognized Outbreak Periods.Pathogens (Basel, Switzerland) · 2026Article
- Interepidemic Rift Valley fever in East Africa: the recent risk landscape and projected impacts of global change.Proceedings. Biological sciences · 2026Article
- Utility of TaqMan Array Cards for detection of acute febrile illness etiologies in patients suspected of viral hemorrhagic fever infections.BMC infectious diseases · 2025Article
- Rift Valley Fever Outbreak Investigation Associated with a Dairy Farm Abortion Storm, Mbarara District, Western Uganda, 2023.Viruses · 2025Article
- Has the epidemiologic conundrum of Rift Valley fever changed?Tropical animal health and production · 2025Review
- Spatial and temporal analysis of Rift Valley fever outbreaks in livestock in Uganda: a retrospective study from 2013 to 2022.BMC veterinary research · 2025Article
- Advancements and Challenges in Addressing Zoonotic Viral Infections with Epidemic and Pandemic Threats.Viruses · 2025Review
- Rift Valley Fever in Rwanda Is Urging for Enhancing Global Health Security Through Multisectoral One Health Strategy.Microorganisms · 2025Review
- Have you heard of Rift Valley fever? Findings from a multi-country study in East and Central Africa.PloS one · 2025Article
- Knowledge, attitudes, practices (KAP), and risk factors toward zoonotic diseases among smallholder livestock farmers in Bugesera district of Rwanda.Frontiers in public health · 2025Article
- Rift Valley fever seroprevalence and risk factors among human populations in Uganda's cattle corridor: a cross-sectional study.BMJ public health · 2025Article
- Rift Valley fever outbreak among animal handlers in Kinyogoga Village, Nakaseke District, Central Uganda: A case study.PLOS global public health · 2025Article
- One Health investigation and response to a nationwide outbreak of Rift Valley fever in Rwanda - March to December 2022.One health (Amsterdam, Netherlands) · 2024Article
- Genomic Epidemiology of Rift Valley Fever Virus Involved in the 2018 and 2022 Outbreaks in Livestock in Rwanda.Viruses · 2024Article
- Severe morbidity and hospital-based mortality from Rift Valley fever disease between November 2017 and March 2020 among humans in Uganda.Virology journal · 2024Article
- Cross border population movements across three East African states: Implications for disease surveillance and response.PLOS global public health · 2024Article
- Rift Valley Fever outbreaks in the East African Community: insights from ProMed data (2010-2024).Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
21 authors at 3 institutions in 2 countries.
Funding
Abstract
Rift Valley fever (RVF) is a zoonotic disease of public health and economic importance. Uganda has reported sporadic outbreaks of RVF in both humans and animals across the country, especially in the southwestern part of the "cattle corridor" through an established viral hemorrhagic fever surveillance system. We report 52 human cases of laboratory-confirmed RVF from 2017 to 2020. The case fatality rate was 42%. Among those infected, 92% were males and 90% were adults (≥ 18 years). Clinical symptoms were characterized by fever (69%), unexplained bleeding (69%), headache (51%), abdominal pain (49%), and nausea and vomiting (46%). Most of the cases (95%) originated from central and western districts that are part of the cattle corridor of Uganda, where the main risk factor was direct contact with livestock (P = 0.009). Other predictors of RVF positivity were determined to be male gender (P = 0.001) and being a butcher (P = 0.04). Next-generation sequencing identified the predominant Ugandan clade as Kenya-2, observed previously across East Africa. There is need for further investigation and research into the effect and spread of this neglected tropical disease in Uganda and the rest of Africa. Control measures such as promoting vaccination and limiting animal-human transmission could be explored to reduce the impact of RVF in Uganda and globally.
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Registered trials
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