Evidence map›Paper›PMID 36913499›Full record

ArticleCirculation2023

Perm1 Protects the Heart From Pressure Overload-Induced Dysfunction by Promoting Oxidative Metabolism.

Shizuko Tachibana, Nam-Kyung Yu, Ruixia Li, Carolina Fernandez-Costa, Alex Liang, Janet Choi, Dayoen Jung, Changchun Xiao, Anastasia Kralli, John R Yates and 2 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. PERM1 regulates mitochondrial energetics through O-GlcNAcylation in the heart.Journal of molecular and cellular cardiology · 2025
    Article
  8. Cardiac maturation.Journal of molecular and cellular cardiology · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shizuko TachibanaDivision of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.).
Nam-Kyung YuDepartments of Molecular Medicine and Neurobiology (N.-K.Y., C.F.-C., J.R.Y.), The Scripps Research Institute, La Jolla, CA.
Ruixia LiDivision of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.).
Carolina Fernandez-CostaDepartments of Molecular Medicine and Neurobiology (N.-K.Y., C.F.-C., J.R.Y.), The Scripps Research Institute, La Jolla, CA.
Alex LiangDivision of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.).
Janet ChoiDivision of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.).
Dayoen JungDivision of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.).
Changchun XiaoDepartment of Immunology and Microbiology (C.X.), The Scripps Research Institute, La Jolla, CA.
Anastasia KralliDepartment of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD (A.K.).
John R YatesDepartments of Molecular Medicine and Neurobiology (N.-K.Y., C.F.-C., J.R.Y.), The Scripps Research Institute, La Jolla, CA.
Robert S RossDivision of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.).ORCID 0000-0003-2195-8982
Yoshitake ChoDivision of Cardiovascular Medicine, Department of Medicine, University of California, San Diego, La Jolla (S.T., R.L., A.L., J.C., D.J., R.S.R., Y.C.).ORCID 0000-0002-7161-3248

Funding

Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
The role of obscurin and Obsl1 as key determinants for diastolic functionR01HL152251 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHO, YOSHITAKE, LANGE, STEPHAN · 2021 to 2024
$2.3M
Estrogen-Related Receptor Pathways in Skeletal MuscleR01DK105126 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI KRALLI, ANASTASIA · 2015 to 2019
$1.9M
PERM in Cardiac FunctionR01HL151239 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHO, YOSHITAKE, ROSS, ROBERT SCOTT · 2020 to 2023
$1.6M
NHLBI NIH HHS R01 HL151239NHLBI NIH HHS R01 HL152251NHLBI NIH HHS T32 HL007444NIDDK NIH HHS R01 DK105126
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HeartHeart FailureOxidative StressAnimalsCell RespirationMiceMice, Inbred C57BLMuscle ProteinsMyocardiumMuscle ProteinsPERM1 protein, mouseMICOSmitochondriaoxidative metabolismPerm1pressure overload

Identifiers

PMID36913499
PMCPMC10018424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.