Evidence map›Paper›PMID 36913466›Full record

ArticleThe Journal of nutrition2023

Dietary Supplement Use in Women Diagnosed with Breast Cancer.

Meg Hauer, Anthony M Rossi, Betsy C Wertheim, Hilary B Kleppel, Jennifer W Bea, Janet L Funk

Erratum issuedAbstract read
In one paragraph

Article in The Journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Meg HauerCollege of Medicine, University of Arizona, Tucson, AZ, USA.
Anthony M RossiHonors College, University of Arizona, Tucson, AZ, USA.
Betsy C WertheimUniversity of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA.
Hilary B KleppelHonors College, University of Arizona, Tucson, AZ, USA.
Jennifer W BeaUniversity of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA; Department of Health Promotion Sciences, Mel & Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA; Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ, USA.
Janet L FunkUniversity of Arizona Cancer Center, University of Arizona, Tucson, AZ, USA; Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ, USA; School of Nutritional Sciences & Wellness, College of Agriculture and Life Sciences, University of Arizona, Tucson, AZ, USA. Electronic address: jfunk@u.arizona.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamins, minerals, and natural product (NP)-derived dietary supplements are commonly used among women with breast cancer, where interactions with treatments and the disease are possible, emphasizing the importance for health care providers to be aware of supplement use.

objectivesThe study aimed to investigate current vitamin/mineral (VM) and NP supplement use among those diagnosed with breast cancer, including usage based on tumor type or concurrent breast cancer treatments and primary information sources for specific supplements.

methodsSocial media recruiting to complete an online questionnaire self-reporting current VM and NP use and breast cancer diagnosis and treatment information primarily attracted US participants. Analyses, including multivariate logistic regression, were performed on 1271 women who self-reported breast cancer diagnosis and completed the survey.

resultsMost participants reported current VM (89.5%) and NP (67.7%) use, with 46.5% (VM) and 26.7% (NP) using at least 3 products concurrently. Top-reported (>15% prevalence) products were vitamin D, calcium, multivitamin, and vitamin C for VM and probiotics, turmeric, fish oil/omega-3 fatty acids, melatonin, and cannabis for NP. Overall, VM or NP use was higher among those with hormone receptor-positive tumors. Although overall NP use did not differ according to current breast cancer treatments, VM use was significantly less common among those currently undergoing chemotherapy or radiation, but higher with current endocrine therapy. Among current chemotherapy users, specific VM and NP supplements with possible adverse effects were still used by 23% of respondents. Medical providers were the primary information source for VM, whereas NP information sources were more varied.

conclusionsBecause women diagnosed with breast cancer commonly reported concurrent use of multiple VM and NP supplements, including those with known or underexplored risks (or benefits) in breast cancer, it is important for health care providers to inquire about and facilitate discussions regarding supplement use in this population.

Indexed as

Dietary SupplementsNeoplasmsLogistic ModelsMineralsSurveys and QuestionnairesVitaminsMineralsVitaminsbotanicalbreast cancerchemotherapydietary supplementendocrine therapyhormone receptormineralnatural productvitamin

Identifiers

PMID36913466
PMCPMC10196584

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.