ArticlePLoS neglected tropical diseases2023
Seasonal variation of diarrhoeal pathogens among Guinea-Bissauan children under five years of age.
Article in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 14 citations in OpenAlex.
- Methodology for measuring behavior change dictates the perceived effectiveness of school-based WASH interventions.Frontiers in public health · 2026Trial
- Variability of enteric pathogen infections by season and meteorological conditions in a low-income, urban setting in Mozambique.PLOS global public health · 2026Article
- EnteroaggregativeEcoSal Plus · 2025Review
- Variability of enteric pathogen infections by season and meteorological conditions in a low-income, urban setting in Mozambique.medRxiv : the preprint server for health sciences · 2025Article
- Trends and seasonal variation in gastrointestinal infections in Tanzania: Analysis of 5-year DHIS2 data toward implementing the sampling cycles and metagenomic analyses.IJID regions · 2025Article
- Rapid, season-specific PCR testing versus traditional diagnostics for pneumonia in the emergency department.BMC pulmonary medicine · 2025Article
- Distribution and prevalence ofJournal of medical microbiology · 2025Article
- Influence of hydrometeorological risk factors on child diarrhea and enteropathogens in rural Bangladesh.PLoS neglected tropical diseases · 2024Article
- Prevalence and Antibiotic Susceptibility of Pathogenic Enterobacteria Strains from Three Biotopes in the City of Ouagadougou (Burkina Faso).Infection and drug resistance · 2024Article
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Authors and funding
6 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiarrhoea remains a major cause of childhood morbidity and mortality in low-income countries (LICs). The frequency of diarrhoeal episodes may vary by season, yet few prospective cohort studies have examined seasonal variation among various diarrhoeal pathogens using multiplex qPCR to analyse bacterial, viral and parasitic pathogens.
methodsWe combined our recent qPCR data of diarrhoeal pathogens (nine bacterial, five viral and four parasitic) among Guinea-Bissauan children under five years old with individual background data, dividing by season. The associations of season (dry winter and rainy summer) and the various pathogens were explored among infants (0-11 months) and young children (12-59 months) and those with and without diarrhoea.
resultsMany bacterial pathogens, especially EAEC, ETEC and Campylobacter, and parasitic Cryptosporidium, prevailed in the rainy season, whereas many viruses, particularly the adenovirus, astrovirus and rotavirus proved common in the dry season. Noroviruses were found constantly throughout the year. Seasonal variation was observed in both age groups.
conclusionIn childhood diarrhoea in a West African LIC, seasonal variation appears to favour EAEC, ETEC, and Cryptosporidium in the rainy and viral pathogens in the dry season.
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