Evidence map›Paper›PMID 36913351›Full record

ArticlePloS one2023

Topological data analysis of human brain networks through order statistics.

Soumya Das, D Vijay Anand, Moo K Chung

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Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Soumya DasDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, United States of America.ORCID 0000-0002-6690-3128
D Vijay AnandDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, United States of America.
Moo K ChungDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, United States of America.ORCID 0000-0003-2852-9670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the common topological characteristics of the human brain network across a population is central to understanding brain functions. The abstraction of human connectome as a graph has been pivotal in gaining insights on the topological properties of the brain network. The development of group-level statistical inference procedures in brain graphs while accounting for the heterogeneity and randomness still remains a difficult task. In this study, we develop a robust statistical framework based on persistent homology using the order statistics for analyzing brain networks. The use of order statistics greatly simplifies the computation of the persistent barcodes. We validate the proposed methods using comprehensive simulation studies and subsequently apply to the resting-state functional magnetic resonance images. We found a statistically significant topological difference between the male and female brain networks.

Indexed as

BrainConnectomeFemaleHumansMagnetic Resonance ImagingMaleNerve Net

Identifiers

PMID36913351
PMCPMC10010566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.