Evidence map›Paper›PMID 36913150›Full record

ReviewMolecular and cellular biochemistry2023

Emerging roles and therapeutic potentials of ferroptosis: from the perspective of 11 human body organ systems.

Yaochong Tan, Xueting Dong, Donglin Zhuang, Buzi Cao, Hua Jiang, Qingnan He, Mingyi Zhao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yaochong TanDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.ORCID http://orcid.org/0000-0003-2913-4355
Xueting DongDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China.ORCID http://orcid.org/0000-0003-4334-4316
Donglin ZhuangDepartment of Structural Heart Disease, National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, China.ORCID http://orcid.org/0000-0002-9367-7891
Buzi CaoHunan Normal University School of Medicine, Changsha, 410081, Hunan, China.ORCID http://orcid.org/0000-0001-6838-3712
Hua JiangGuangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, Guangdong, China. jiang_hua18@sina.cn.ORCID http://orcid.org/0000-0002-4552-0785
Qingnan HeDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China. heqn2629@163.com.ORCID http://orcid.org/0000-0001-5229-9583
Mingyi ZhaoDepartment of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, 410013, Hunan, China. zhao_mingyi@csu.edu.cn.ORCID http://orcid.org/0000-0002-2884-0736
Central South University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNGuangzhou Women and Children Medical Center · CNHunan Normal University · CN

Funding

National Natural Science Foundation of China 81970248National Natural Science Foundation of Hunan Province 2020JJ4833
6 · The paper itself

Abstract

Since ferroptosis was first described as an iron-dependent cell death pattern in 2012, there has been increasing interest in ferroptosis research. In view of the immense potential of ferroptosis in treatment efficacy and its rapid development in recent years, it is essential to track and summarize the latest research in this field. However, few writers have been able to draw on any systematic investigation into this field based on human body organ systems. Hence, in this review, we provide a comprehensive description of the latest progress in unveiling the roles and functions, as well as the therapeutic potential of ferroptosis, in treating diseases from the aspects of 11 human body organ systems (including the nervous system, respiratory system, digestive system, urinary system, reproductive system, integumentary system, skeletal system, immune system, cardiovascular system, muscular system, and endocrine system) in the hope of providing references for further understanding the pathogenesis of related diseases and bringing an innovative train of thought for reformative clinical treatment.

Indexed as

FerroptosisCell DeathHuman BodyHumansIronIronCell deathClinical treatmentFerroptosisHuman body organ systems

Identifiers

PMID36913150
OpenAlexW4324020135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.