Evidence map›Paper›PMID 36913066›Full record

ReviewPlanta2023

Enhancing the quality of staple food crops through CRISPR/Cas-mediated site-directed mutagenesis.

Olawale Samuel Adeyinka, Bushra Tabassum, Brice Landry Koloko, Ifedayo Victor Ogungbe

Abstract readReview
PubMed Publisher
In one paragraph

Review in Planta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Enhanced Yield ofPlants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Review
  4. CRISPR/Cas Technology Revolutionizes Crop Breeding.Plants (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Olawale Samuel AdeyinkaDepartment of Chemistry, Physics and Atmospheric Sciences Jackson State University, Jackson, MS, 39217, USA. adeyinka.olawale@gmail.com.ORCID http://orcid.org/0000-0003-1430-9538
Bushra TabassumSchool of Biological Sciences, University of the Punjab, Lahore, Pakistan.
Brice Landry KolokoUniversity Institute of Technology, University of Douala, Douala, Cameroon.
Ifedayo Victor OgungbeDepartment of Chemistry, Physics and Atmospheric Sciences Jackson State University, Jackson, MS, 39217, USA.
Jackson State University · USUniversity of Douala · CMUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MAIN

conclusionThe enhancement of CRISPR-Cas gene editing with robust nuclease activity promotes genetic modification of desirable agronomic traits, such as resistance to pathogens, drought tolerance, nutritional value, and yield-related traits in crops. The genetic diversity of food crops has reduced tremendously over the past twelve millennia due to plant domestication. This reduction presents significant challenges for the future especially considering the risks posed by global climate change to food production. While crops with improved phenotypes have been generated through crossbreeding, mutation breeding, and transgenic breeding over the years, improving phenotypic traits through precise genetic diversification has been challenging. The challenges are broadly associated with the randomness of genetic recombination and conventional mutagenesis. This review highlights how emerging gene-editing technologies reduce the burden and time necessary for developing desired traits in plants. Our focus is to provide readers with an overview of the advances in CRISPR-Cas-based genome editing for crop improvement. The use of CRISPR-Cas systems in generating genetic diversity to enhance the quality and nutritional value of staple food crops is discussed. We also outlined recent applications of CRISPR-Cas in developing pest-resistant crops and removing unwanted traits, such as allergenicity from crops. Genome editing tools continue to evolve and present unprecedented opportunities to enhance crop germplasm via precise mutations at the desired loci of the plant genome.

Indexed as

CRISPR-Cas SystemsCrops, AgriculturalPlant BreedingGene EditingGenome, PlantMutagenesis, Site-DirectedPlants, Genetically ModifiedCRISPR/CasCrop improvementGenetic diversityMutagenesisTransgenic breeding

Identifiers

PMID36913066
OpenAlexW4324020882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.