Evidence map›Paper›PMID 36912923›Full record

ArticleEuropean radiology2023

Early shoulder-girdle MRI findings in severe COVID-19-related intensive care unit-acquired weakness: a prospective cohort study.

Camille Daste, Fadila Mihoubi, Alexandra Roren, Alina Dumitrache, Nicolas Carlier, Sarah Benghanem, Aude Ruttimann, Jean-Paul Mira, Frédéric Pène, Nicolas Roche and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Camille Daste *Université de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
Fadila Mihoubi *INSERM UMR-S 1153, Centre de Recherche Épidémiologie Et Statistique Paris (CRESS), ECaMO Team, 75004, Paris, France.
Alexandra RorenAP-HP. Centre-Université de Paris Cité, Hôpital Cochin, Service de Rééducation Et de Réadaptation de L'Appareil Locomoteur Et Des Pathologies du Rachis, 27, Rue du Faubourg Saint-Jacques, 75014, Paris, France.
Alina DumitracheAP-HP. Centre-Université de Paris Cité, Hôpital Corentin Celton, Service de Rééducation Et de Réadaptation, 92130, Issy-Les-Moulineaux, France.
Nicolas CarlierAP-HP. Centre-Université de Paris Cité, Hôpital Cochin, Service de Pneumologie, 75014, Paris, France.
Sarah BenghanemUniversité de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
Aude RuttimannAP-HP. Centre-Université de Paris Cité, Hôpital Cochin, Service de Médecine Intensive Et Réanimation, 75014, Paris, France.
Jean-Paul MiraUniversité de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
Frédéric PèneUniversité de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
Nicolas RocheUniversité de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
Paul SerorLaboratoire d'électroneuromyographie, 146 Av Ledru Rollin, 75011, Paris, France.
Christelle NguyenUniversité de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
François RannouUniversité de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
Jean-Luc Drapé *Université de Paris, Faculté de Santé, UFR de Médecine, Paris, France.
Marie-Martine Lefèvre-Colau *Université de Paris, Faculté de Santé, UFR de Médecine, Paris, France. marie-martine.lefevre-colau@aphp.fr.ORCID http://orcid.org/0000-0002-7493-1225
Inserm · FRUniversité Paris Cité · FRCentre National de la Recherche Scientifique · FRLaboratoire d'Électronique, Antennes et Télécommunications · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe clinical and early shoulder-girdle MR imaging findings in severe COVID-19-related intensive care unit-acquired weakness (ICU-AW) after ICU discharge.

methodsA single-center prospective cohort study of all consecutive patients with COVID-19-related ICU-AW from November 2020 to June 2021. All patients underwent similar clinical evaluations and shoulder-girdle MRI within the first month and then 3 months (± 1 month) after ICU discharge.

resultsWe included 25 patients (14 males; mean [SD] age 62.4 [12.5]). Within the first month after ICU discharge, all patients showed severe proximal predominant bilateral muscular weakness (mean Medical Research Council total score = 46.5/60 [10.1]) associated with bilateral, peripheral muscular edema-like MRI signals of the shoulder girdle in 23/25 (92%) patients. At 3 months, 21/25 (84%) patients showed complete or quasi-complete resolution of proximal muscular weakness (mean Medical Research Council total score > 48/60) and 23/25 (92%) complete resolution of MRI signals of the shoulder girdle, but 12/20 (60%) patients experienced shoulder pain and/or shoulder dysfunction.

conclusionsEarly shoulder-girdle MRI findings in COVID-19-related ICU-AW included muscular edema-like peripheral signal intensities, without fatty muscle involution or muscle necrosis, with favorable evolution at 3 months. Precocious MRI can help clinicians distinguish critical illness myopathy from alternative, more severe diagnoses and can be useful in the care of patients discharged from intensive care with ICU-AW. KEY POINTS: • We describe the clinical and shoulder-girdle MRI findings of COVID-19-related severe intensive care unit-acquired weakness. • This information can be used by clinicians to achieve a nearly specific diagnosis, distinguish alternative diagnoses, assess functional prognosis, and select the more appropriate health care rehabilitation and shoulder impairment treatment.

Indexed as

COVID-19ShoulderHumansIntensive Care UnitsMagnetic Resonance ImagingMaleMiddle AgedMuscle WeaknessProspective StudiesCOVID-19Intensive care unitMagnetic resonance imagingMuscle weaknessShoulder

Identifiers

PMID36912923
PMCPMC10010198
OpenAlexW4324020324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.