Evidence map›Paper›PMID 36912329›Full record

ArticleInfection control and hospital epidemiology2023

Coronavirus disease 2019 (COVID-19) outbreak on an in-patient medical unit associated with unrecognized exposures in common areas-Epidemiological and whole-genome sequencing investigation.

Dylan C Kain, Sandra Isabel, Mariana Abdulnoor, Karel Boissinot, Richard De Borja, Amanda Filkin, Bernard Lam, Jason Li, Ilinca Lungu, Liz McCreight and 9 more

Abstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Dylan C KainDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-5890-2742
Sandra IsabelDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-7277-4150
Mariana AbdulnoorDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Karel BoissinotDepartment of Laboratory Medicine, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-0389-4145
Richard De BorjaOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Amanda FilkinOccupational Health, Sinai Health, Toronto, Ontario, Canada.
Bernard LamOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Jason LiOntario Institute for Cancer Research, Toronto, Ontario, Canada.ORCID 0000-0002-9174-2514
Ilinca LunguOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Liz McCreightInfection Prevention and Control, Sinai Health, Toronto, Ontario, Canada.
Allison McGeerDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Tony MazzulliDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Aimee PatersonLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.
Philip ZuzarteOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Felicia VincelliOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Cassandra BergwerffOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Ramzi FattouhDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-6573-6367
Jared T SimpsonOntario Institute for Cancer Research, Toronto, Ontario, Canada.
Jennie JohnstoneDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hospital outbreaks have been common and devastating during the coronavirus disease 2019 (COVID-19) pandemic. Understanding SARS-CoV-2 transmission in these environments is critical for preventing and managing outbreaks.

designOutbreak investigation through epidemiological mapping and whole-genome sequencing phylogeny.

settingHospital in-patient medical unit outbreak in Toronto, Canada, from November 2020 to January 2021.

participantsThe outbreak involved 8 patients and 10 staff and was associated with 3 patient deaths.

resultsPatients being cared for in geriatric chairs at the nursing station were at high risk for both acquiring and transmitting SARS-CoV-2 to other patients and staff. Furthermore, given the informal nature of these transmissions, they were not initially recognized, which led to further transmission and missing the opportunity for preventative COVID-19 therapies.

conclusionsDuring outbreak prevention and management, the risk of informal patient care settings, such as geriatric chairs, should be considered. During high-risk periods or during outbreaks, efforts should be made to care for patients in their rooms when possible.

Indexed as

COVID-19AgedCanadaDisease OutbreaksHospitalsHumansSARS-CoV-2

Identifiers

PMID36912329
PMCPMC10665866

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.