SynthesisThe British journal of surgery2023
Timing of symptomatic venous thromboembolism after surgery: meta-analysis.
Synthesis in The British journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Artificial intelligence for venous thromboembolism risk stratification in surgical patients: a systematic review.Journal of thrombosis and thrombolysis · 2026Pooled it
- Aspirin for the extended prevention of venous thromboembolism: a meta-analysis and trial sequential analysis.Scientific reports · 2025Pooled it
- Advances and Challenges in the Application of Novel Oral Anticoagulants for Venous Thromboembolism Prevention Following Colorectal Cancer Surgery.Journal of gastrointestinal cancer · 2025Pooled it
- Comparing the efficacy and safety of thromboprophylaxis with enoxaparin versus normal saline after liver transplantation: randomized clinical trial.The British journal of surgery · 2025Trial
- Role of extended venous thromboembolism prophylaxis in patients with colorectal neoplasia who underwent minimally invasive colorectal surgery within an enhanced recovery after surgery protocol.Surgical endoscopy · 2026Article
- Association Between Recent Mechanical Risk Factors for Venous Thrombosis and Young-Onset Cryptogenic Ischemic Stroke.Stroke · 2026Article
- Short-Term Complications Are Rare After Cholesteatoma Surgery.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026Article
- Does defect size matter? Risk of venous thromboembolism and pulmonary embolism after ventral hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Impact of thromboprophylaxis timing and duration on thromboembolism and bleeding in metabolic bariatric surgery.BJS open · 2026Article
- Extended venous thromboembolism prophylaxis after bariatric surgery: the potential role of aspirin.Annals of medicine and surgery (2012) · 2026Article
- Persistent Hypercoagulability After Radical Prostatectomy: Biomarker Dynamics and Implications for Individualized Thromboprophylaxis.Journal of clinical medicine · 2026Review
- Venous Thromboembolism (VTE) Risk Stratification in Otolaryngology: Socioeconomic and Subspecialty Insights.Laryngoscope investigative otolaryngology · 2026Article
- Risk for clinical venous thromboembolism and major bleeding after surgery for lumbar spinal stenosis: a retrospective matched register-based cohort study with 462,533 individuals.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Delayed surgery can increase the preoperative DVT risk in patients with tibial plateau fractures: a retrospective association analysis.Thrombosis journal · 2025Article
- Influence of patient's weight and body mass index on presentation, time of onset, and impact of postoperative venous thromboembolism (RIETE registry).Journal of thrombosis and thrombolysis · 2025Observational
- Article
- Association of coagulation-related indicators with postoperative venous thromboembolism occurrence in patients with pituitary tumors.Scientific reports · 2025Article
- Extended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.The British journal of surgery · 2025Observational
- Development and validation of a nomogram prediction model for perioperative deep vein thrombosis risk in arthroplasty: a retrospective study.Frontiers in medicine · 2025Article
- Venous thromboembolism in patients undergoing surgery for lung cancer: a post hoc analysis of the Cancer-VTE Registry.Japanese journal of clinical oncology · 2024Article
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Authors and funding
17 authors at 8 institutions in 6 countries.
Funding
Abstract
backgroundThe timing at which venous thromboembolism (VTE) occurs after major surgery has major implications for the optimal duration of thromboprophylaxis. The aim of this study was to perform a systematic review and meta-analysis of the timing of postoperative VTE up to 4 weeks after surgery.
methodsA systematic search of MEDLINE, Scopus, and CINAHL databases was performed between 1 January 2009 and 1 April 2022. Prospective studies that recruited patients who underwent a surgical procedure and reported at least 20 symptomatic, postoperative VTE events by time were included. Two reviewers independently selected studies according to the eligibility criteria, extracted data, and evaluated risk of bias. Data were analysed with a Poisson regression model, and the GRADE approach was used to rate the certainty of evidence.
resultsSome 6258 studies were evaluated, of which 22 (11 general, 5 urological, 4 mixed, and 2 orthopaedic postoperative surgical populations; total 1 864 875 patients and 24 927 VTE events) were eligible. Pooled evidence of moderate certainty showed that 47.1 per cent of the VTE events occurred during the first, 26.9 per cent during the second, 15.8 per cent during the third, and 10.1 per cent during the fourth week after surgery. The timing of VTE was consistent between individual studies.
conclusionAlthough nearly half of symptomatic VTE events in first 4 weeks occur during the first postoperative week, a substantial number of events occur several weeks after surgery. These data will inform clinicians and guideline developers about the duration of postoperative thromboprophylaxis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.