Evidence map›Paper›PMID 36912114›Full record

ArticleTwin research and human genetics : the official journal of the International Society for Twin Studies2023

Nature, Nurture, and the Meaning of Educational Attainment: Differences by Sex and Socioeconomic Status.

Thalida Em Arpawong, Margaret Gatz, Catalina Zavala, Tara L Gruenewald, Ellen E Walters, Carol A Prescott

Abstract readTwin Study
In one paragraph

Article in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thalida Em ArpawongLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-9671-9535
Margaret GatzDepartment of Psychology, Dornsife School of Letters, Arts and Sciences, University of Southern California, Los Angeles, California, USA.
Catalina ZavalaDepartment of Psychology, Dornsife School of Letters, Arts and Sciences, University of Southern California, Los Angeles, California, USA.
Tara L GruenewaldSchool of Psychology, Chapman University, Orange, California, USA.
Ellen E WaltersCenter for Economic and Social Research, Dornsife School of Letters, Arts and Sciences, University of Southern California, Los Angeles, California, USA.
Carol A PrescottLeonard Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.

Funding

USC/UCLA Center on Biodemography &Population HealthP30AG017265 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE · 1999 to 2026
$17.9M
Risk for Alzheimer's Disease and Cognitive Decline in Project TALENTR01AG056163 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PRESCOTT, CAROL ARLENE · 2016 to 2020
$5.4M
School Quality and Racial Disparities in Alzheimer's Disease in Project TalentRF1AG056164 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANLY, JENNIFER JAIE · 2016 to 2019
$3.7M
Clarifying risk and protective factors for dementia with the Interplay of Genes and Environment in Multiple Studies (IGEMS) consortiumR01AG060470 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2018 to 2022
$3.6M
A 55-Year Follow-up Study of Project TALENT Twins and Siblings R01AG043656 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PRESCOTT, CAROL ARLENE · 2013 to 2014
$923k
NIA NIH HHS P30 AG017265NIA NIH HHS R01 AG043656NIA NIH HHS R01 AG056163NIA NIH HHS R01 AG060470NIA NIH HHS RF1 AG056164
6 · The paper itself

Abstract

Estimated heritability of educational attainment (EA) varies widely, from 23% to 80%, with growing evidence suggesting the degree to which genetic variation contributes to individual differences in EA is highly dependent upon situational factors. We aimed to decompose EA into influences attributable to genetic propensity and to environmental context and their interplay, while considering influences of rearing household economic status (HES) and sex. We use the Project Talent Twin and Sibling Study, drawn from the population-representative cohort of high school students assessed in 1960 and followed through 2014, to ages 68-72. Data from 3552 twins and siblings from 1741 families were analyzed using multilevel regression and multiple group structural equation models. Individuals from less-advantaged backgrounds had lower EA and less variation. Genetic variance accounted for 51% of the total variance, but within women and men, 40% and 58% of the total variance respectively. Men had stable genetic variance on EA across all HES strata, whereas high HES women showed the same level of genetic influence as men, and lower HES women had constrained genetic influence on EA. Unexpectedly, middle HES women showed the largest constraints in genetic influence on EA. Shared family environment appears to make an outsized contribution to greater variability for women in this middle stratum and whether they pursue more EA. Implications are that without considering early life opportunity, genetic studies on education may mischaracterize sex differences because education reflects different degrees of genetic and environmental influences for women and men.

Indexed as

Academic SuccessTwinsAgedEducational StatusFemaleHumansMaleSiblingsSocial ClassGene-by-environmentparental socioeconomic statussex differences

Identifiers

PMID36912114
PMCPMC10497722

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.