Evidence map›Paper›PMID 36911702›Full record

ArticleFrontiers in immunology2023

Transcriptional reprogramming of natural killer cells by vaccinia virus shows both distinct and conserved features with mCMV.

Delphine M Depierreux, Geoffrey L Smith, Brian J Ferguson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Delphine M DepierreuxDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.
Geoffrey L SmithDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.
Brian J FergusonDepartment of Pathology, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GB

Funding

Medical Research Council MR/M019810/1
6 · The paper itself

Abstract

Natural killer (NK) cells have an established role in controlling poxvirus infection and there is a growing interest to exploit their capabilities in the context of poxvirus-based oncolytic therapy and vaccination. How NK cells respond to poxvirus-infected cells to become activated is not well established. To address this knowledge gap, we studied the NK cell response to vaccinia virus (VACV)

Indexed as

PoxviridaeVacciniaAnimalsCytokinesHumansKiller Cells, NaturalMiceVaccinia virusCytokinesMCMV: murine CMVNK cellsNK memorytranscriptomicsvaccinationvaccinia

Identifiers

PMID36911702
PMCPMC9995584
OpenAlexW4321600940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.