Evidence map›Paper›PMID 36911665›Full record

ArticleFrontiers in immunology2023

Bruton's tyrosine kinase inhibition attenuates disease progression by reducing renal immune cell invasion in mice with hemolytic-uremic syndrome.

Sarah Kröller, Bianka Wissuwa, Sophie Dennhardt, Nadine Krieg, Christoph Thiemermann, Christoph Daniel, Kerstin Amann, Florian Gunzer, Sina M Coldewey

Abstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah KröllerDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
Bianka WissuwaDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
Sophie DennhardtDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
Nadine KriegDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
Christoph ThiemermannWilliam Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Christoph DanielDepartment of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Kerstin AmannDepartment of Nephropathology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg, Erlangen, Germany.
Florian GunzerDepartment of Hospital Infection Control, University Hospital Carl Gustav Carus, TU Dresden, Dresden, Germany.
Sina M ColdeweyDepartment of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemolytic-uremic syndrome (HUS) can occur as a complication of an infection with Shiga-toxin (Stx)-producing

Indexed as

Acute Kidney InjuryHemolytic-Uremic SyndromeShiga-Toxigenic Escherichia coliAgammaglobulinaemia Tyrosine KinaseAnimalsEpithelial CellsKidneyMiceAgammaglobulinaemia Tyrosine Kinaseacalabrutinibacute kidney injuryanimal modelBruton’s tyrosine kinasehemolytic-uremic syndromeibrutinibinflammation

Identifiers

PMID36911665
PMCPMC9995712

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.