Evidence map›Paper›PMID 36911662›Full record

ArticleFrontiers in immunology2023

The effect of sodium thiosulfate on immune cell metabolism during porcine hemorrhage and resuscitation.

Eva-Maria Wolfschmitt, Melanie Hogg, Josef Albert Vogt, Fabian Zink, Ulrich Wachter, Felix Hezel, Xiaomin Zhang, Andrea Hoffmann, Michael Gröger, Clair Hartmann and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Ex VivoBiomolecules · 2024
    Article
  3. BayesianMetabolites · 2023
    Article
  4. Article
  5. Frontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Eva-Maria WolfschmittInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Melanie HoggInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Josef Albert VogtInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Fabian ZinkInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Ulrich WachterInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Felix HezelInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Xiaomin ZhangInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Andrea HoffmannInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Michael GrögerInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Clair HartmannClinic for Anesthesia and Intensive Care, University Hospital Ulm, Ulm, Germany.
Holger GässlerDepartment of Anaesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Federal Armed Forces Hospital Ulm, Ulm, Germany.
Thomas DatzmannInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Tamara MerzInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Andreas HellmannInstitute of Analytical and Bioanalytical Chemistry, Ulm University, Ulm, Germany.
Christine KranzInstitute of Analytical and Bioanalytical Chemistry, Ulm University, Ulm, Germany.
Enrico CalziaInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
Peter RadermacherInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
David Alexander Christian MessererInstitute of Anesthesiological Pathophysiology and Process Engineering, University Hospital Ulm, Ulm, Germany.
University Hospital Ulm · DEUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Sodium thiosulfate (Na Methods: After 3 h of hemorrhage, anesthetized and surgically instrumented swine underwent resuscitation up to a maximum of 68 h. At 2 h of shock, animals randomly received vehicle or Na Results: PBMCs showed significantly higher mitochondrial O Conclusion: In a porcine model of hemorrhage and resuscitation, Na

Indexed as

Shock, HemorrhagicAnimalsBayes TheoremHemorrhageLeukocytes, MononuclearLipidsSwineThiosulfatesLipidssodium thiosulfateThiosulfateshemorrhagic shockhydrogen sulfideimmunometabolisminnate immunitymetabolic flux analysismetabolic modelingmitochondrial respirationreactive oxygen species

Identifiers

PMID36911662
PMCPMC9996035
OpenAlexW4321596380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.