Evidence map›Paper›PMID 36911660›Full record

ArticleFrontiers in immunology2023

Canine peripheral blood TCRαβ T cell atlas: Identification of diverse subsets including CD8A

Maria Eschke, Peter F Moore, Haiyang Chang, Gottfried Alber, Stefan M Keller

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. FcεRγI promotes canine CD8 chimeric antigen receptor T cell cytotoxicity through a Syk-NF-κB axis.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A review of CD4Veterinary immunology and immunopathology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Canine peripheral non-conventional TCRαβFrontiers in immunology · 2024
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Maria EschkeInstitute of Immunology/Molecular Pathogenesis, Center for Biotechnology and Biomedicine, College of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
Peter F MooreDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA, United States.
Haiyang ChangDepartment of Mathematics and Statistics, University of Guelph, Guelph, ON, Canada.
Gottfried AlberInstitute of Immunology/Molecular Pathogenesis, Center for Biotechnology and Biomedicine, College of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
Stefan M KellerDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA, United States.
Leipzig University · DEUniversity of California, Davis · USUniversity of Guelph · CA

Funding

Acquisition of Covaris E220 and Sciclone G3 systems for high throughput sequencinS10OD010786 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COMAI, LUCA · 2012 to 2012
$311k
NIH HHS S10 OD010786
6 · The paper itself

Abstract

The dog is valued as a companion animal and increasingly recognized as a model for human disorders. Given the importance of T cells in health and disease, comprehensive knowledge of canine T cells can contribute to our understanding of pathogenesis mechanisms and inform the development of new treatment strategies. However, the diversity of canine T cells is still poorly understood mainly due to the lack of species-reactive antibodies for use in flow cytometry. The aim of this study was to generate a detailed atlas of peripheral blood TCRαβ

Indexed as

Mucosal-Associated Invariant T CellsReceptors, Antigen, T-Cell, alpha-betaAnimalsCell DifferentiationDogsHumansT-Lymphocytes, RegulatoryTranscriptomeReceptors, Antigen, T-Cell, alpha-betacanine T cellsdogimmune repertoireinnate-like T cellsMAIT-like cellsperipheral bloodsingle-cell RNA-sequencingTCRαβ

Identifiers

PMID36911660
PMCPMC9995359
OpenAlexW4321600723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.