Evidence map›Paper›PMID 36911643›Full record

ArticleClinical case reports2023

Heinz body hemolysis following extended use phenazopyridine in a post-HCT patient with hemorrhagic cystitis: An old problem for a new generation.

Asmaa Ferdjallah, Susie Long, Vanessa Dayton, Ashish O Gupta

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Asmaa FerdjallahDivision of Blood and Marrow Transplant and Cellular Therapy, Department of Pediatrics University of Minnesota Minneapolis Minnesota USA.ORCID https://orcid.org/0000-0001-9250-6014
Susie LongMHealth Fairview, Acute Care Pharmacy Services Minneapolis Minnesota USA.
Vanessa DaytonDepartment of Pathology, Hematopathology University of Minnesota Minneapolis Minnesota USA.
Ashish O GuptaDivision of Blood and Marrow Transplant and Cellular Therapy, Department of Pediatrics University of Minnesota Minneapolis Minnesota USA.ORCID https://orcid.org/0000-0001-5679-5533

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemorrhagic cystitis is a common complication following the use of cyclophosphamide. Associated dysuria can be painful and there are few good options to relieve pain. Phenazopyridine has historically been utilized for dysuria and is available over the counter. However, it is associated with hematologic side effects with prolonged use. Here we present a case of a patient who developed Heinz body hemolysis following prolonged administration of phenazopyridine to treat cyclophosphamide-induced hemorrhagic cystitis following hematopoietic stem cell transplant.

Indexed as

Heinz bodyhemolysishemorrhagic cystitispediatricsphenazopyridine

Identifiers

PMID36911643
PMCPMC9992140

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.