Evidence map›Paper›PMID 36911614›Full record

ArticleFrontiers in surgery2023

Establishment of clinical predictive model based on the study of influence factors in patients with colorectal polyps.

Yu Huang, Yating Liu, Xu Yin, Tianpeng Zhang, Yaoguang Hao, Pengfei Zhang, Yang Yang, Zhihan Gao, Siyu Liu, Suyang Yu and 2 more

Abstract read
In one paragraph

Article in Frontiers in surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Yu HuangDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Yating LiuDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Xu YinDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Tianpeng ZhangDepartment of Second Anorectal, Shijiazhuang Hospital of Traditional Chinese Medicine, Shijiazhuang, China.
Yaoguang HaoDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Pengfei ZhangDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Yang YangDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Zhihan GaoDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Siyu LiuDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Suyang YuDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Hongyan LiDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Guiying WangDepartment of Gastrointestinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) is the most common gastrointestinal malignancy and is generally thought to be caused by the transformation of colorectal polyps. It has been shown that early detection and removal of colorectal polyps may reduce the mortality and morbidity of colorectal cancer. Objective: Based on the risk factors associated with colorectal polyps, an individualized clinical prediction model was built to predict and evaluate the possibility of developing colorectal polyp. Methods: A case-control study was conducted. Clinical data were collected from 475 patients who underwent colonoscopy at the Third Hospital of Hebei Medical University from 2020 to 2021. All clinical data were then divided into training sets and validation sets by using R software (7:3). A multivariate logistic analysis was performed to identify the factors associated with colorectal polyps according to the training set, and a predictive nomogram was created by R software based on the multivariate analysis. The results were internally validated by receiver operating characteristic (ROC) curves, calibration curves, and externally validated by validation sets. Results: Multivariate logistic regression analysis showed that age (OR = 1.047, 95% CI = 1.029-1.065), history of cystic polyp (OR = 7.596, 95% CI = 0.976-59.129), and history of colorectal diverticulums (OR = 2.548, 95% CI = 1.209-5.366) were independent risk factors for colorectal polyps. History of constipation (OR = 0.457, 95% CI = 0.268-0.799) and fruit consumption (OR = 0.613, 95% CI 0.350-1.037) were protective factors for colorectal polyps. The nomogram demonstrated good accuracy for predicting colorectal polyps, with both C index and AUC being 0.747 (95% CI = 0.692-0.801). The calibration curves showed good agreement between the predicted risk by the nomogram and real outcomes. Both internal and external validation of the model showed good results. Conclusion: In our study, the nomogram prediction model is reliable and accurate, which can help early clinical screening of patients with high-risk colorectal polyps, improve polyp detection rate, and reduce the incidence of colorectal cancer (CRC).

Indexed as

influencing factorsintestinal polypsintestinal tumornomogramprevention

Identifiers

PMID36911614
PMCPMC9995385

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.