Evidence map›Paper›PMID 36911577›Full record

ArticleContemporary clinical trials communications2023

Design of Lung Transplant Go (LTGO): A randomized controlled trial evaluating the efficacy of a telerehabilitation behavioral exercise intervention to improve physical activity, physical function, and blood pressure control after lung transplantation.

Melissa L Vendetti, Seol Ju Esther Moon, Christopher C Imes, Andrea Hergenroeder, Frank Sciurba, Elizabeth Lendermon, Joseph Pilewski, Dianxu Ren, Bambang Parmanto, Barbara Dewhirst and 5 more

Open access · goldAbstract read
In one paragraph

Article in Contemporary clinical trials communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Exploring Factors Associated with Sleep Quality After Lung Transplantation.Progress in transplantation (Aliso Viejo, Calif.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Melissa L VendettiUniversity of Pittsburgh, School of Nursing, Department of Acute and Tertiary Care, Pittsburgh, PA, USA.
Seol Ju Esther MoonUniversity of Pittsburgh, School of Nursing, Department of Acute and Tertiary Care, Pittsburgh, PA, USA.
Christopher C ImesUniversity of Pittsburgh, School of Nursing, Department of Acute and Tertiary Care, Pittsburgh, PA, USA.
Andrea HergenroederUniversity of Pittsburgh, School of Health and Rehabilitation Sciences, Department of Physical Therapy, Pittsburgh, PA, USA.
Frank SciurbaUniversity of Pittsburgh, School of Medicine, Department of Medicine, Division of Pulmonary Allergy Critical Care Medicine, Pittsburgh, PA, USA.
Elizabeth LendermonUniversity of Pittsburgh, School of Medicine, Department of Medicine, Division of Pulmonary Allergy Critical Care Medicine, Pittsburgh, PA, USA.
Joseph PilewskiUniversity of Pittsburgh, School of Medicine, Department of Medicine, Division of Pulmonary Allergy Critical Care Medicine, Pittsburgh, PA, USA.
Dianxu RenUniversity of Pittsburgh, School of Nursing, Department of Health and Community Systems, Pittsburgh, PA, USA.
Bambang ParmantoUniversity of Pittsburgh, School of Health and Rehabilitation Sciences, Department of Health Information Management, Pittsburgh, PA, USA.
Barbara DewhirstUniversity of Pittsburgh, School of Nursing, Department of Acute and Tertiary Care, Pittsburgh, PA, USA.
Bryan WilleyUniversity of Pittsburgh, School of Nursing, Department of Acute and Tertiary Care, Pittsburgh, PA, USA.
Kristen JonesUniversity of Pittsburgh, School of Nursing, Department of Acute and Tertiary Care, Pittsburgh, PA, USA.
Matthew R MorrellUniversity of Utah Health, Internal Medicine, Division of Pulmonary and Critical Care, Salt Lake City, UT, USA.
Pablo SanchezUniversity of Pittsburgh, School of Medicine, Department of Surgery, Division of Cardiothoracic Surgery, Pittsburgh, PA, USA.
Annette DeVito DabbsUniversity of Pittsburgh, School of Nursing, Department of Acute and Tertiary Care, Pittsburgh, PA, USA.
University of Pittsburgh · USUniversity of Utah · US

Funding

Lung Transplant Go (LTGO): Improving Self-Management of Exercise After Lung TransplantationR01NR017196 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DE VITO DABBS, ANNETTE J · 2018 to 2021
$2.2M
NINR NIH HHS R01 NR017196
6 · The paper itself

Abstract

Background: Lung transplantation is an established treatment option for persons with advanced lung disease. After transplantation, lung function typically returns to near normal levels, however exercise capacity remains low due to chronic deconditioning, limited physical function, and inactive lifestyles which undermine the intended benefits of the highly selective, resource-intensive transplant procedure. Pulmonary rehabilitation is recommended to improve fitness and activity tolerance, however due to multiple barriers, lung transplant recipients either never participate, or fail to complete, pulmonary rehabilitation programs. Purpose: To describe the design of Lung Transplant Go (LTGO), a trial modified for the remote environment based on recommendations to preserve trial integrity during COVID. The aims are to evaluate a behavioral exercise intervention to improve physical function, physical activity, and blood pressure control in lung transplant recipients conducted safely and effectively using a telerehabilitation (telerehab) platform, and to explore the role of potential mediators and moderators of the relationship between LTGO and outcomes. Methods: Single-site, 2-group randomized controlled trial with lung transplant recipients randomized 1:1 to either the LTGO intervention (a 2-phased, supervised, telerehab behavioral exercise program), or to enhanced usual care (activity tracking and monthly newsletters). All study activities, including intervention delivery, recruitment, consenting, assessment, and data collection, will be performed remotely. Conclusion: If efficacious, this fully scalable and replicable telerehab intervention could be efficiently translated to reach large numbers of lung recipients to improve and sustain self-management of exercise habits by overcoming barriers to participation in existing, in-person pulmonary rehabilitation programs.

Indexed as

Behavior change techniquesLung transplantRandomized controlled trialSelf-monitoringTelerehabilitation

Identifiers

PMID36911577
PMCPMC9999171
OpenAlexW4323038530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.