Evidence map›Paper›PMID 36911270›Full record

ArticleEClinicalMedicine2023

The international experience of in-situ recovery of the DCD heart: a multicentre retrospective observational study.

John Louca, Marco Öchsner, Ashish Shah, Jordan Hoffman, Francisco González Vilchez, Iris Garrido, Mario Royo-Villanova, Beatriz Domínguez-Gil, Deane Smith, Leslie James and 14 more

Abstract read
In one paragraph

Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Spanish Center's Early Experience With Donation Following Circulatory Death in Heart Transplantation.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Current status and challenges of DCD heart transplantation in the Asia-Pacific region.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. The role of temporary mechanical circulatory support in heart failure.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

John LoucaUniversity of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Rd, Cambridge CB2 0SP, UK.
Marco ÖchsnerUniversity of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Rd, Cambridge CB2 0SP, UK.
Ashish ShahVanderbilt Heart Transplant Unit 1215, 21st Ave, Nashville, Tennessee 37232, USA.
Jordan HoffmanVanderbilt Heart Transplant Unit 1215, 21st Ave, Nashville, Tennessee 37232, USA.
Francisco González VilchezSpanish Registry on Heart Transplantation, Madrid, Spain.
Iris GarridoHospital Universitario Virgen de La Arrixaca, Ctra. Madrid-Cartagena, s/n, El Palmar, Murcia 30120, Spain.
Mario Royo-VillanovaHospital Universitario Virgen de La Arrixaca, Ctra. Madrid-Cartagena, s/n, El Palmar, Murcia 30120, Spain.
Beatriz Domínguez-GilOrganización Nacional de Trasplantes, Madrid, Spain.
Deane SmithDepartment of Cardiothoracic Surgery, Langone, 1300 Franklin Avenue, Suite ML-2, Garden City, NY, USA.
Leslie JamesDepartment of Cardiothoracic Surgery, Langone, 1300 Franklin Avenue, Suite ML-2, Garden City, NY, USA.
Nader MoazamiDepartment of Cardiothoracic Surgery, Langone, 1300 Franklin Avenue, Suite ML-2, Garden City, NY, USA.
Filip RegaDepartments of Cardiac Surgery and Cardiology, The University Hospital Leuven, Leuven, Belgium.
Janne BrouckaertDepartments of Cardiac Surgery and Cardiology, The University Hospital Leuven, Leuven, Belgium.
Johan Van CleemputDepartments of Cardiac Surgery and Cardiology, The University Hospital Leuven, Leuven, Belgium.
Katrien VandendriesscheDepartments of Cardiac Surgery and Cardiology, The University Hospital Leuven, Leuven, Belgium.
Vincent Tchana-SatoDepartment of Cardiovascular Surgery, CHU Liege, Liege, Belgium.
Diawara BandiougouDepartment of Cardiovascular Surgery, CHU Liege, Liege, Belgium.
Marian UrbanDepartment of Cardiothoracic Surgery, University of Nebraska Medical Centre, 2410 Atherholt Road, Omaha, NE, USA.
Alex ManaraThe Intensive Care Unit, Southmead Hospital, North Bristol NHS Trust, Bristol BS 10 5NB, UK.
Marius BermanRoyal Papworth Hospital Biomedical Campus, Cambridge, CB2 0AY, UK.
Simon MesserGolden Jubilee Hospital, Agamermnon Street, Glasgow G81 4DY, UK.
Stephen LargeRoyal Papworth Hospital Biomedical Campus, Cambridge, CB2 0AY, UK.
WISPGm
WISPG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Heart transplantation is an effective treatment offering the best recovery in both quality and quantity of life in those affected by refractory, severe heart failure. However, transplantation is limited by donor organ availability. The reintroduction of heart donation after the circulatory determination of death ( Method: This was a multicentre retrospective observational study. Outcomes included functional warm ischaemic time, use of mechanical support immediately following transplantation, perioperative and long-term actuarial survival and incidence of acute rejection requiring treatment. 157 Findings: taNRP resulted in a 23% increase in heart transplantation activity. Survival was similar in the taNRP group when compared to DBD. 30-day survival was 96.8% ([92.5%-98.6%] 95% CI, n = 156), 1-year survival was 93.2% ([87.7%-96.3%] 95% CI, n = 72) and 5-year survival was 84.3% ([69.6%-92.2%] 95% CI, n = 13). Interpretation: Our study suggests that taNRP provides a significant boost to heart transplantation activity. The survival rates of Funding: None of the authors have a financial relationship with a commercial entity that has an interest in the subject.

Indexed as

Cold storageCSDBDDCDDonation after brain deathDonation after circulatory determination of deathDonation after neurological deathESMPEx-situ machine perfusionHeart beating donationIn-situ perfusionNon heart beating donationtaNRPThoraco-abdominal nromothermic regional perfusion

Identifiers

PMID36911270
PMCPMC9995283

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.