Evidence map›Paper›PMID 36911240›Full record

ReviewF1000Research2023

A review of recent advances in the diagnosis of cardiac amyloidosis, treatment of its cardiac complications, and disease-modifying therapies.

Maharshi Raval, Sajid Siddiq, Kamal Sharma, Labdhi Sanghvi, Akhil Jain, Sagar Patel, Jaahnavee Trivedi, Kanishka Uttam Chandani, Dhriti Patel, Rupak Desai

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Maharshi RavalDepartment of Internal Medicine, New York Medical College, Valhalla, New York, USA.ORCID 0000-0002-3016-0078
Sajid SiddiqDepartment of Cardiology, New York Medical College, Valhalla, New York, USA.
Kamal SharmaDepartment of Cardiology, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
Labdhi SanghviDepartment of Pediatrics, Ahmedabad Municipal Corporation Medical Education Trust Medical College, Ahmedabad, Gujarat, India.
Akhil JainDepartment of Internal Medicine, Mercy Fitzgerald Hospital, Darby, Pennsylvania, USA.
Sagar PatelDepartment of Internal Medicine, New York Medical College, Valhalla, New York, USA.
Jaahnavee TrivediDepartment of Internal Medicine, New York Medical College, Valhalla, New York, USA.
Kanishka Uttam ChandaniDepartment of Internal Medicine, New York Medical College, Valhalla, New York, USA.
Dhriti PatelDepartment of Medicine, B.J. Medical College and Civil Hospital, Ahmedabad, Gujarat, USA.
Rupak DesaiIndependent Researcher, Atlanta, USA.
New York Medical College · USB.J. Medical College · INEducation Trust · USMercy Fitzgerald Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac amyloidosis (CA), a significant condition resulting in infiltrative cardiomyopathy and heart failure with preserved ejection fraction (HFpEF), is caused by extracellular deposition of amyloid fibrils in the heart. Even though this has been known for an extended period, its prevalence in elderly patients with heart failure is increasingly being recognized. Recent advances in diagnosis with non-invasive methods like technetium pyrophosphate-labeled cardiac scintigraphy (i.e., Tc-PYP scan) and treatment options with tafamidis have played a pivotal role in awareness of the burden of this disease. Management of cardiac complications like heart failure, atrial arrhythmias, conduction block, ventricular arrhythmias, coronary artery disease, and aortic stenosis is now more critical than ever. We aim to review and outline the recent advances in diagnoses of CA. We also review management strategies for cardiac complications of CA with a brief summary of disease-modifying therapies.

Indexed as

AmyloidosisCardiomyopathiesHeart FailureAgedHeartHumansStroke VolumeAL amyloidosisATTR amyloidosisbone scintigraphycardiac amyloidosisheart failuretafamidis

Identifiers

PMID36911240
PMCPMC9995736
OpenAlexW4321372741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.