Evidence map›Paper›PMID 36910947›Full record

ArticleACS omega2023

Synthesis of C3,C6-Diaryl 7-Azaindoles via One-Pot Suzuki-Miyaura Cross-Coupling Reaction and Evaluation of Their HIV-1 Integrase Inhibitory Activity.

Savio Cardoza, Pooja Yadav, Abhishek Ajmani, Parthasarathi Das, Vibha Tandon

Abstract read
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In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Savio CardozaSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.
Pooja YadavSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.
Abhishek AjmaniSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.
Parthasarathi DasDepartment of Chemistry and Chemical Biology, Indian Institute of Technology (Indian School of Mines), Dhanbad 826004, India.ORCID https://orcid.org/0000-0002-9306-4956
Vibha TandonSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.ORCID https://orcid.org/0000-0001-6146-937X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a continuing demand of new inhibitors of HIV-1 Integrase (HIV-1 IN) due to mutations of HIV-1. This study aims to develop the synthesis of 3,6-diaryl 7-azaindoles and introspect the role of aryl groups on the strand transfer (ST) inhibition of HIV-1 IN. An efficient and chemo-selective one-pot method is established for the synthesis of the unexplored diverse C3 → C6 diaryl 7-azaindoles starting from 6-chloro-3-iodo-

Identifiers

PMID36910947
PMCPMC9996623

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.