Evidence map›Paper›PMID 36910632›Full record

ArticleFrontiers in oncology2023

Artificial-intelligence-based computed tomography histogram analysis predicting tumor invasiveness of lung adenocarcinomas manifesting as radiological part-solid nodules.

Jian Gao, Qingyi Qi, Hao Li, Zhenfan Wang, Zewen Sun, Sida Cheng, Jie Yu, Yaqi Zeng, Nan Hong, Dawei Wang and 4 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jian GaoDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Qingyi QiDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Hao LiDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Zhenfan WangDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Zewen SunDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Sida ChengDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Jie YuDepartment of Thoracic Surgery, Qingdao Women and Children's Hospital, Qingdao, China.
Yaqi ZengDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Nan HongDepartment of Radiology, Peking University People's Hospital, Beijing, China.
Dawei WangInstitute of Advanced Research, Infervision Medical Technology Co., Ltd, Beijing, China.
Huiyang WangInstitute of Advanced Research, Infervision Medical Technology Co., Ltd, Beijing, China.
Feng YangDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Xiao LiDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.
Yun LiDepartment of Thoracic Surgery, Peking University People's Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tumor invasiveness plays a key role in determining surgical strategy and patient prognosis in clinical practice. The study aimed to explore artificial-intelligence-based computed tomography (CT) histogram indicators significantly related to the invasion status of lung adenocarcinoma appearing as part-solid nodules (PSNs), and to construct radiomics models for prediction of tumor invasiveness. Methods: We identified surgically resected lung adenocarcinomas manifesting as PSNs in Peking University People's Hospital from January 2014 to October 2019. Tumors were categorized as adenocarcinoma Results: In total, 299 AIS/MIAs and 889 IACs were included. In the training cohort, multivariate logistic regression analysis demonstrated that age [odds ratio (OR), 1.020; 95% CI, 1.004-1.037; Conclusion: We developed an AI-based histogram model, which could reliably predict tumor invasiveness in lung adenocarcinoma manifesting as PSNs. This finding would provide promising value in guiding the precision management of PSNs in the daily practice.

Indexed as

CT histogramlung adenocarcinomapart-solid nodulethree-dimensional indextumor invasiveness

Identifiers

PMID36910632
PMCPMC9996279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.