Evidence map›Paper›PMID 36910527›Full record

ArticleFrontiers in cardiovascular medicine2023

The gut microbiota in experimental abdominal aortic aneurysm.

Jie Xiao, Zhanjie Wei, Chuanlei Yang, Shilin Dai, Xiancan Wang, Yuqiang Shang

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Evidence for a Role of Gut Microbiota and Probiotics in Aneurysmal Pathogenesis and Possible Therapeutics: A Systematic Review of the Literature.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Pooled it
  2. Article
  3. Review
  4. Frontiers in microbiology · 2026
    Review
  5. Article
  6. The Critical Role ofReviews in cardiovascular medicine · 2025
    Review
  7. Article
  8. Article
  9. Infection and immunity · 2024
    Article
  10. Article
  11. Cholesterol-Lowering Effect of Polysaccharides fromFoods (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie XiaoDepartment of Cardiovascular Surgery, Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.
Zhanjie WeiDepartment of General Surgery, Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.
Chuanlei YangDepartment of Cardiovascular Surgery, Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.
Shilin DaiDepartment of Cardiovascular Surgery, Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.
Xiancan WangDepartment of Cardiovascular Surgery, Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.
Yuqiang ShangDepartment of Cardiovascular Surgery, Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Abdominal aortic aneurysm (AAA) is a life-threatening disease and there are no effective treatments to inhibit aneurysm progression and rupture. The gut microbiota has been increasingly recognized, as a new therapeutic target, because of its role in host homeostasis. However, the role of the gut microbiota in AAA has not been clarified. Therefore, we performed 16S rRNA analysis to determine and compare the composition of the gut microbiota between AAA and control groups. Methods: We used the classical angiotensin-II induced AAA mouse model to investigate the role of gut microbiota and abdominal aortic aneurysm. The mice were randomly assigned to 2 groups: the control ( Results: The levels of Conclusion: Alterations in the gut microbiota may be associated with the formation of AAA.

Indexed as

16S rRNAabdominal aortic aneurysmAkkermansiaBacteroidetesgut microbiota

Identifiers

PMID36910527
PMCPMC9992639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.