Evidence map›Paper›PMID 36910309›Full record

ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2023

Expression of the Fab enzymes (Fab I and Fab Z) from

Ndeye Fatou Kane, Mutinda Cleophas Kyama, Joseph Kangethe Nganga, Ahmed Hassanali, Mouhamadou Diallo, Francis T Kimani

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ndeye Fatou KaneJKUAT Biochemistry Department, Pan African University Institute of Basic Sciences and Technology Innovation, P.O. Box 62000-00200, Nairobi, Kenya.ORCID 0000-0002-3846-9109
Mutinda Cleophas KyamaDepartment of Medical Laboratory Sciences, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000-00200, Nairobi, Kenya.
Joseph Kangethe NgangaBiochemistry Department, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 3878-00100, Nairobi, Kenya.
Ahmed HassanaliSchool of Pure and Applied Sciences Chemistry Department, Kenyatta University, P O Box: 43844-00100, Nairobi, Kenya.
Mouhamadou DialloTeaching Hospital A. Le Dantec, Bacteriology and Virology Laboratory, Malaria Unit, Cheikh Anta Diop University, Dakar, Senegal.
Francis T KimaniMalaria Center in Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Jomo Kenyatta University of Agriculture and Technology · KECheikh Anta Diop University · SNKenya Medical Research Institute · KEKenyatta University · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence and spread of drug resistance of the malaria parasite to the main treatment emphasize the need to develop new antimalarial drugs. In this context, the fatty acid biosynthesis (FAS_II) pathway of the malaria parasite is one of the ideal targets due to its crucial role in parasite survival. In this study, we report the expression and the affinity binding of Fab_I and Fab_Z after exposure to the parasite with different extracts of the

Indexed as

Artemisia afraDrugs screeningFab_IFab_ZGene expression

Identifiers

PMID36910309
PMCPMC9998800
OpenAlexW4304893560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.