Evidence map›Paper›PMID 36910163›Full record

ArticleTherapeutic advances in gastroenterology2023

Short- and long-term follow-up after fecal microbiota transplantation as treatment for recurrent

Emilie E van Lingen, Simon S M D Baunwall, Simone S C Lieberknecht, Nicolas N Benech, Gianluca G Ianiro, Harry H Sokol, Alessandro A Gasbarrini, Giovanni G Cammarota, Marcel M K Eriksen, Andrea A E van der Meulen-de Jong and 5 more

Abstract read
In one paragraph

Article in Therapeutic advances in gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Guideline
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  11. Inflammatory bowel disease andTherapeutic advances in gastroenterology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Emilie E van LingenDepartment of Gastroenterology and Hepatology, Leiden University Medical Center (LUMC), Albinusdreef 2, Leiden, ZA 2333, The Netherlands.ORCID https://orcid.org/0000-0002-3927-0345
Simon S M D BaunwallDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-5135-7435
Simone S C LieberknechtDepartment of Internal Medicine, Infectious Diseases, Goethe University Frankfurt, Frankfurt am Main, Germany.
Nicolas N BenechSorbonne Université, INSERM, Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint Antoine Hospital, Gastroenterology département, F-75012 Paris, France.
Gianluca G IaniroInternal Medicine and Gastroenterology, Fondazione Policlinico Universitario Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.ORCID https://orcid.org/0000-0002-8318-0515
Harry H SokolGastroenterology Département, INSERM, Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint Antoine Hospital, Sorbonne Université, Paris, France.
Alessandro A GasbarriniInternal Medicine and Gastroenterology, Fondazione Policlinico Universitario Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.
Giovanni G CammarotaInternal Medicine and Gastroenterology, Fondazione Policlinico Universitario Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.
Marcel M K EriksenDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Andrea A E van der Meulen-de JongDepartment of Gastroenterology and Hepatology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Elizabeth E M TerveerDepartment of Medical Microbiology, LUMC, Leiden, The Netherlands.
Hein H W VerspagetDepartment of Gastroenterology and Hepatology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Maria M VehreschildDepartment of Internal Medicine, Infectious Diseases, Goethe University Frankfurt, Frankfurt am Main, Germany.
Christian C L HvasDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Josbert J J KellerDepartment of Gastroenterology and Hepatology, Leiden University Medical Center (LUMC), Albinusdreef 2, Leiden, ZA 2333, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with inflammatory bowel disease (IBD) are at an increased risk of developing Objectives: We performed a multicentre cohort study in patients with IBD who received fecal microbiota transplantation (FMT) for recurrent CDI (rCDI), to further investigate factors that influence the clinical outcome and course of both rCDI and IBD. Design: This is a multicentre cohort study conducted in five European FMT centres. Methods: Adult IBD patients treated with FMT for rCDI were studied. Cure was defined as clinical resolution of diarrhoea or diarrhoea with a negative Results: In total, 113 IBD patients underwent FMT because of rCDI. Mean age of the patients was 48 years; 64% had ulcerative colitis. Concomitant rCDI was associated with an IBD flare in 54%, of whom 63% had received IBD remission-induction therapy prior to FMT. All FMT procedures were preceded by vancomycin treatment, 40% of patients received FMT Conclusion: FMT for rCDI in IBD patients is safe and effective, and IBD exacerbation after FMT is infrequent. Further studies should investigate the effects on IBD course following FMT.

Indexed as

fecal microbiota transplantationinflammatory bowel diseaserecurrent Clostridioides difficile infectionstool banking

Identifiers

PMID36910163
PMCPMC9998411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.