Evidence map›Paper›PMID 36910139›Full record

ReviewFrontiers in cell and developmental biology2023

Non-canonical autophagy in aging and age-related diseases.

Anita V Kumar, Joslyn Mills

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Full length TECPR1 displays 'cis' Dysferlin domain architecture.bioRxiv : the preprint server for biology · 2026
    Article
  2. Physiological responses to mask-associated COFrontiers in public health · 2026
    Review
  3. Review
  4. Article
  5. Mechanisms and roles of membrane-anchored ATG8s.Frontiers in cell and developmental biology · 2025
    Review
  6. Functional Relationships between L1CAM, LC3, ATG12, and Aβ.International journal of molecular sciences · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Autophagy: Regulator of cell death.Cell death & disease · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anita V KumarMolecular Biology, Cell Biology and Biochemistry Department, Brown University, Providence, RI, United States.
Joslyn MillsMolecular Biology, Cell Biology and Biochemistry Department, Brown University, Providence, RI, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy, one of the arms of proteostasis, influences aging and age-related diseases. Recently, the discovery of additional roles of autophagy-related proteins in non-canonical degradation and secretion has revealed alternative fates of autophagic cargo. Some of these non-canonical pathways have been linked to neurodegenerative diseases and improving the understanding of this link is crucial for their potential targetability in aging and age-related diseases. This review discusses recent investigations of the involvement of non-canonical autophagy players and pathways in age-related diseases that are now beginning to be discovered. Unraveling these pathways and their relation to classical autophagy could unearth a fascinating new layer of proteostasis regulation during normal aging and in longevity.

Indexed as

agingLANDOLAP (LC3 associated phagocytosis)neurodegenerative diseasaesnon-canonical autophagysecretory autophagy

Identifiers

PMID36910139
PMCPMC9995962

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.