ArticleJournal of thoracic disease2023
Risk factors, complications and costs of prolonged air leak after video-assisted thoracoscopic surgery for primary lung cancer.
Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Sealing strength and application efficiency of the microbubble fibrin sealant technique: influence of PGA sheet type in an ex vivo porcine lung model.General thoracic and cardiovascular surgery · 2026Article
- Intraoperative Volume Decay Measured Through Mechanical Ventilation as a Predictor of Prolonged Postoperative Air Leak After Uniportal Video-Assisted Thoracic Surgery Lung Resection.Journal of personalized medicine · 2026Article
- Can Artificial Intelligence Interpret Pulmonary Function Tests and Predict Prolonged Air Leaks After Lung Resection.Cancers · 2026Article
- Microbubble fibrin sealant application technique for prolonged air leak after anatomical lung resection: a retrospective comparative study.Journal of thoracic disease · 2026Article
- Financial Burden of Postoperative Adverse Events Following Lobectomy: Cost Analysis From 10 High-Volume Canadian Hospitals.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026Article
- Polyglycolic Acid Aerostatic Patch for Air Leak Management: Results from a Decade of Pulmonary Resections Using Propensity-Score Weighting.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Machine learning-based prediction of prolonged air leak after uniportal video-assisted thoracic surgery segmentectomy.Frontiers in oncology · 2026Article
- CT-based emphysema score is associated with prolonged air leak after lung resection: a retrospective cohort study.Journal of thoracic disease · 2025Article
- Article
- Biocompatibility of a novel lung sealant based on functionalized polyoxazolines in an ovine model of parenchymal lung injury.Journal of thoracic disease · 2025Article
- Data-driven prediction of prolonged air leak after video-assisted thoracoscopic surgery for lung cancer: Development and validation of machine-learning-based models using real-world data through the ePath system.Learning health systems · 2025Article
- Early Postoperative Patient-Reported Outcomes of Sarcopenia Versus Nonsarcopenia in Patients Undergoing Video-Assisted Thoracoscopic Surgery for Lung Cancer.Annals of surgical oncology · 2025Article
- Risk factors and clinical impact of prolonged air leak following video-assisted thoracoscopic surgery: a retrospective cohort study.Frontiers in medicine · 2025Article
- Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy.Journal of cardiothoracic surgery · 2024Review
- A New Functional Threshold for Minimally Invasive Lobectomy.Annals of surgery · 2024Article
- Comparison of watershed analysis with indocyanine green fluorescence staining and modified inflation-deflation method in single-port thoracoscopic complex pulmonary segmentectomy.Journal of thoracic disease · 2024Article
- Exploring indications for anatomic partial lobectomy in the modern era.Journal of thoracic disease · 2024Article
- Zero-leak prediction during major lung resection aiming for minimal chest drainage duration: a retrospective analysis.Journal of cardiothoracic surgery · 2024Article
- The safety and efficacy of additional chest tube placement in patients with prolonged air leaks after pulmonary resection: a propensity score-matched analysis.Frontiers in medicine · 2024Article
- Article
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6 authors.
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Abstract
Background: Prolonged air leak (PAL) represents a common complication after lung resection. This study aims to analyze the risk factors for the development of a PAL, its impact on the postoperative outcome and to estimate additional treatment costs. Methods: A single center database was queried for all patients scheduled for video-assisted thoracoscopic surgery for primary lung cancer. In total, 957 patients between 2009 and 2021 were analyzed. Exclusion criteria was pneumonectomy. Collected data included demographics and perioperative data (e.g., duration of surgery, postoperative infections, air leak duration etc.). PAL was defined as an air leak lasting for 5 days or longer. The PAL cohort included 103 patients, the non-PAL included 854 patients. Univariate analysis and binomial logistic regression were performed. Cost calculation was performed using available data from prior publications to estimate treatment costs. Results: Male sex, chronic obstructive pulmonary disease (COPD) and low body mass index (BMI) showed to be risk factors for the development of postoperative PAL (P<0.001). Using these risk factors, a risk prediction score for PAL has been established. A subgroup analysis showed a significantly higher rate of sarcopenia in patients with PAL (P<0.001). The mean duration until removal of chest drains and length of stay (LOS) was significantly longer in the PAL cohort (14.2 Conclusions: PAL is a frequent complication that prolongs the LOS after thoracic surgery and, according to the literature, results in elevated readmission rates, leading to excess health care costs. Risk factors for PAL are well established. Preoperative treatment of sarcopenia and dismal nutritional status might alter the risk. As measures to prevent PAL are otherwise limited, guidelines for effective management of PAL need to be established.
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