ReviewJournal of thoracic disease2023
Intraoperative prevention and conservative management of postoperative prolonged air leak after lung resection: a systematic review.
Review in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prediction models for prolonged air leak after pulmonary surgery: a systematic review and critical appraisal.Frontiers in oncology · 2026Pooled it
- Air leaks management using polymeric hydrogel matrix after thoracoscopic lung segmentectomy: a single-center prospective randomized trial with a cost-effective analysis.Updates in surgery · 2026Trial
- Comparison of 40% Glucose Solution and Autologous Blood Patch Pleurodesis for the Treatment of Postoperative Air Leak After Lung Resections: A Prospective Randomized Controlled Study.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Trial
- Association of Wearable Activity Monitors and Digital Drainage Device With Daily Ambulation and Length of Stay Among Pulmonary Resection Patients: A Prospective, Randomized Controlled Study.Thoracic cancer · 2025Trial
- [Phrenic Nerve Cryotherapy for Preventing Prolonged Air Leak During VATS Lobectomy].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025Trial
- Diaphragm-Directed Strategies for Prolonged Air Leak Prevention After Lung Resection: A Narrative Review of the Residual Pleural Space Paradigm.Journal of clinical medicine · 2026Review
- Comparison of the perioperative outcomes between uniportal thoracoscopic lobectomy and segmentectomy for early-stage non-small-cell lung cancer in Japan.Surgical endoscopy · 2026Observational
- The expert consensus document on minimally invasive upper lobectomy for lung cancer in China.Journal of thoracic disease · 2026Review
- Pleural Sealants in Pneumothorax Surgery: A Step Forward or Added Expense?Journal of chest surgery · 2026Article
- Article
- Suction Impact on Chest Drain Duration After Lung Resection: A Study Using Digital Drainage Systems.Journal of clinical medicine · 2026Article
- Article
- Material Use for Air Leakage Prevention Post-Lung Resection: Insights from Real-World Data in Japan.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
- From Alveolar Injury to Precision Perioperative Care: Integrating Molecular Biomarkers and Technology-Enabled Strategies for Prolonged Air Leak After Lung Resection.Mediators of inflammation · 2026Review
- Off-label use of lung sealants: the need for evidence-based guidelines and adequate indications for use.Journal of thoracic disease · 2025Review
- CT-based emphysema score is associated with prolonged air leak after lung resection: a retrospective cohort study.Journal of thoracic disease · 2025Article
- Thoracoscopic Closure of Alveolar Pleural Fistula by Application of Pleural Flap and Polymeric Sealant.Thoracic cancer · 2025Article
- Efficacy of combined silk suture ligation and stapler versus stapler alone for vascular control in uniportal video-assisted thoracoscopic surgery lobectomy.Journal of thoracic disease · 2025Article
- The efficacy of autologous blood patch pleurodesis for prolonged air leak after anatomical lung resection.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Biocompatibility of a novel lung sealant based on functionalized polyoxazolines in an ovine model of parenchymal lung injury.Journal of thoracic disease · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Prolonged air leak (PAL) due to an alveolar-pleural fistula (APF) is the most common complication after lung surgery. PAL is associated with an increased risk of morbidity and mortality, a longer chest tube duration, hence a prolonged hospitalization. Management of PAL may be challenging, and the thoracic surgeon should be aware of the possible therapeutic strategies. Methods: A systematic literature review was performed in PubMed, Cochrane Library, EMBASE, Ovid and Google Scholar. Title, abstract and full-text screening was performed, followed by structured data extraction, methodological quality assessment and Cochrane risk of bias assessment. Inclusion criteria were: case-control studies/randomized controlled trials (RCTs) comparing the new tested method with the standard of care to manage PAL after lung surgery; PAL due to APF; at least 10 patients; English-written papers. Results: A total of 942 initial papers from literature search, resulted in 43 papers after the selection. This systematic review found that the use of intraoperative measures as surgical sealants or pleural tenting, as well as a proper management of the chest drain and the use of blood patch or sclerosant agents seem to reduce postoperative air leaks incidence and/or duration and length of chest drain stay and hospitalization. Conclusions: Different measures have been described in literature to manage or prevent postoperative PAL. Most of them seem to be safe and efficient if compared to the "wait and see" strategy, even if large comparative studies that standardize the intra- and post-operative management of APF after lung resection are lacking and, actually, hard to conceptualize. However, there is a large consensus on the value of a preoperative PAL-risk stratification and on the necessity of tailoring PAL management or prevention's strategy and its timing on each patient's features.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.