ArticleClinical and translational radiation oncology2023
Implementing cone-beam computed tomography-guided online adaptive radiotherapy in cervical cancer.
Article in Clinical and translational radiation oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Prospective multi-institutional study of library-based adaptive radiotherapy for cervical cancer: Evaluation of plan-of-the-day selection and population analysis.Journal of applied clinical medical physics · 2025Trial
- Evaluation of PTV margins with daily iterative online adaptive radiotherapy for postoperative treatment of endometrial and cervical cancer: a prospective single-arm phase 2 study.Radiation oncology (London, England) · 2024Trial
- Cone beam computed tomography guided online adaptive radiotherapy for cervical Cancer: Two-year single-Centre implementation and clinical experience.Technical innovations & patient support in radiation oncology · 2026Article
- An in-house timer for ART-specific extra time in gynecologic pelvic online adaptive radiation therapy.Technical innovations & patient support in radiation oncology · 2026Article
- Improving deep learning organ segmentation accuracy in cone-beam CT-guided radiotherapy using a robust scatter suppression method.Physics and imaging in radiation oncology · 2026Article
- Development of CBCT-Guided Online Adaptive Radiotherapy.Cancers · 2026Review
- Article
- [Daily online adaptive irradiation of bladder tumors with individualized safety margin creation].Magyar onkologia · 2026Article
- A Comparative, Multiobserver Analysis of Nodal Contouring Methods in Pelvic Online Cone Beam-Based Adaptive Radiation Therapy.Advances in radiation oncology · 2026Article
- Potential of margin reduction for cervical cancer radiotherapy in an online adaptive image-guided workflow.Physics and imaging in radiation oncology · 2026Article
- Daily artificial intelligence-assisted adaptive small margin radiotherapy during trimodal therapy of muscle-invasive bladder cancer.Frontiers in oncology · 2026Article
- Impact evaluation of intra-fractional variation on online adaptive radiotherapy for postoperative cervical and endometrial cancer.World journal of clinical oncology · 2025Article
- Multimodal chemoradiotherapy including interstitial brachytherapy enhances outcomes in FIGO stage IVA cervical cancer: a focus on tumor control and quality of life.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Moderately hypofractionated online adaptive radiotherapy (SWIFT-1) in cervical cancer patients: study protocol for a multi-centered, open-label, two-arm, phase III, randomized controlled study.Radiation oncology (London, England) · 2025Article
- Quantitative and automatic plan-of-the-day assessment to facilitate adaptive radiotherapy in cervical cancer.Physics in medicine and biology · 2025Article
- Article
- Physics-based data augmentation for improved training of cone-beam computed tomography auto-segmentation of the female pelvis.Physics and imaging in radiation oncology · 2025Article
- Modeling dosimetric benefits from daily adaptive RT for gynecological cancer patients with and without knowledge-based dose prediction.Journal of applied clinical medical physics · 2025Article
- Assessing population-based to personalized planning strategies for head and neck adaptive radiotherapy.Journal of applied clinical medical physics · 2025Article
- Evaluating CBCT-Guided Adaptive Radiotherapy for Pancreatic Cancer Using Synthetic CBCT Data.Current oncology (Toronto, Ont.) · 2025Article
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12 authors.
Funding
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Abstract
Background and purpose: Adaptive radiotherapy (ART) in locally advanced cervical cancer (LACC) has shown promising outcomes. This study investigated the feasibility of cone-beam computed tomography (CBCT)-guided online ART (oART) for the treatment of LACC. Material and methods: The quality of the automated radiotherapy treatment plans and artificial intelligence (AI)-driven contour delineation for LACC on a novel CBCT-guided oART system were assessed. Dosimetric analysis of 200 simulated oART sessions were compared with standard treatment. Feasibility of oART was assessed from the delivery of 132 oART fractions for the first five clinical LACC patients. The simulated and live oART sessions compared a fixed planning target volume (PTV) margin of 1.5 cm around the uterus-cervix clinical target volume (CTV) with an internal target volume-based approach. Workflow timing measurements were recorded. Results: The automatically-generated 12-field intensity-modulated radiotherapy plans were comparable to manually generated plans. The AI-driven organ-at-risk (OAR) contouring was acceptable requiring, on average, 12.3 min to edit, with the bowel performing least well and rated as unacceptable in 16 % of cases. The treated patients demonstrated a mean PTV D98% (+/-SD) of 96.7 (+/- 0.2)% for the adapted plans and 94.9 (+/- 3.7)% for the non-adapted scheduled plans (p<10 Conclusion: CBCT-guided oART was shown to be feasible with dosimetric benefits for patients with LACC. Further work to analyse potential reductions in PTV margins is ongoing.
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