Evidence map›Paper›PMID 36909732›Full record

ArticleFrontiers in cellular and infection microbiology2023

Comparison of multiple treatment regimens in children with

Miaomiao Liang, Chengbi Zhu, Peipei Zhao, Xiaohui Zhu, Junwei Shi, Bin Yuan

Abstract readNetwork Meta-Analysis
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Antibiotics (Basel, Switzerland) · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Miaomiao LiangDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Chengbi ZhuDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Peipei ZhaoDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Xiaohui ZhuDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Junwei ShiDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Bin YuanDepartment of Pediatrics, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multiple regimens have been widely used in the eradication treatment of Methods: Randomized controlled trials were retrieved. Review Manager 5.4, Stata SE 15 and R 4.0.4 statistical software were used to analyze date. The ranking probability is assessed according to the surfaces under cumulative ranking (SUCRA). Results: 163 studies were eligible for this study, involving 336 arms and 18,257 children, and 10 different interventions. The results showed that the eradication rates of sequential therapy with probiotics (SP), bismuth-containing quadruple (Quadruple) therapy, concomitant therapy and PCN therapy were at least 90%. Cumulative ranking showed that SP therapy had the best eradication effect (SUCRA 92.7%) whereas Bismuth-containing triple therapy (B) had the worst (SUCRA 3.5%). Subgroup analysis suggested that SP therapy ranked first in China and other regions, and the ranking of Triple therapy with probiotics therapy (TP) was equally stable (SUCRA 72.0% Conclusions: As for the eradication treatment of

Indexed as

Helicobacter InfectionsHelicobacter pyloriAnti-Bacterial AgentsBismuthChildDrug Therapy, CombinationHumansTreatment OutcomeAnti-Bacterial AgentsBismuthchildrenefficacyHelicobacter pylorinetwork meta-analysistreatment regimens

Identifiers

PMID36909732
PMCPMC9995679

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.