Evidence map›Paper›PMID 36909676›Full record

ArticleWorld journal of cardiovascular surgery2022

Orthotopic Heart Auto-Transplantation in a Swine Model.

Michael P Rogers, Gregory Fishberger, Nick Martini, Margaret Baldwin, Lei Wang, Wei Chen, Ruisheng Liu, Lucian Lozonschi

Open access · diamondFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of cardiovascular surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Bacteria Endocarditis Caused byComparative medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michael P RogersDivision of Cardiothoracic Surgery, Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Gregory FishbergerDivision of Cardiothoracic Surgery, Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Nick MartiniDivision of Cardiothoracic Surgery, Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Margaret BaldwinDepartment of Comparative Medicine, University of South Florida, Tampa, FL, USA.
Lei WangDepartment of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Wei ChenDepartment of Physics, College of Arts and Sciences, University of South Florida, Tampa, FL, USA.
Ruisheng LiuDepartment of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Lucian LozonschiDivision of Cardiothoracic Surgery, Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
University of South Florida · US

Funding

Tubuloglomerular feedback response in AKI to CKD transitionR01DK134028 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI LIU, RUISHENG · 2022 to 2025
$2.6M
Role of tubuloglomerular feedback in the development of hypertension in diabetesR01HL142814 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIU, RUISHENG · 2019 to 2022
$2.4M
Macula densa NOS1 and transplanted renal graft functionR01DK122050 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI WANG, LEI · 2020 to 2024
$1.6M
Protection of donor kidneys with synchronization modulation electric field (SMEF)R42DK130764 · NIDDK · WR BIOTECH, LLC · PI CHEN, WEI, LIU, RUISHENG · 2022 to 2023
$1.6M
Renal hemodynamics and hypertension during pregnancyR01HL137987 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI LIU, RUISHENG · 2018 to 2021
$1.6M
Tubuloglomerular feedback and salt-sensitive hypertensionR01DK098582 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI LIU, RUISHENG · 2013 to 2016
$1.3M
NHLBI NIH HHS R01 HL137987NHLBI NIH HHS R01 HL142814NIDDK NIH HHS R01 DK098582NIDDK NIH HHS R01 DK122050NIDDK NIH HHS R01 DK134028NIDDK NIH HHS R42 DK130764
6 · The paper itself

Abstract

BACKGROUND AND

aimThe porcine heart bears the best resemblance to the human heart and remains the preferred preclinical model for anatomical, physiological, and medical device studies. In an effort to study phenomena related strictly to ischemia reperfusion and donor preservation protocols, it is essential to avoid the immune responses related to allotransplantation. Orthotopic auto-transplantation is a unique strategy to the field of cardiac transplantation for

methodsA novel method for orthotopic cardiac auto-transplantation in the porcine model was developed and was described herein. Porcine models were used for

resultsA total of five porcine models were used for

conclusionOrthotopic cardiac auto-transplantation in the porcine model is a plausible and technically feasible method for reliable study of ischemia reperfusion injury and donor preservation protocols. Here, we describe methods for both direct orthotopic porcine cardiac auto-transplantations as well as a simplified protocol that can be substituted for full surgical auto-transplantation for the studies of preservation of donor hearts.

Indexed as

Cardiac SurgeryCardiac TransplantationPorcine

Identifiers

PMID36909676
PMCPMC10003613
OpenAlexW4312344965

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read9
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.