Evidence map›Paper›PMID 36909604›Full record

ArticlebioRxiv : the preprint server for biology2023

Pptc7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy.

Natalie M Niemi, Lia R Serrano, Laura K Muehlbauer, Catie Balnis, Keri-Lyn Kozul, Edrees H Rashan, Evgenia Shishkova, Kathryn L Schueler, Mark P Keller, Alan D Attie and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Natalie M NiemiMorgridge Institute for Research, Madison, WI, 53715, USA.
Lia R SerranoDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Laura K MuehlbauerDepartment of Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Catie BalnisDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Keri-Lyn KozulSchool of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia.
Edrees H RashanDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Evgenia ShishkovaDepartment of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Kathryn L SchuelerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Mark P KellerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Alan D AttieDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Julia PaganSchool of Biomedical Sciences, Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia.
Joshua J CoonMorgridge Institute for Research, Madison, WI, 53715, USA.
David J PagliariniMorgridge Institute for Research, Madison, WI, 53715, USA.
University of Wisconsin–Madison · USThe University of Queensland · AUWashington University in St. Louis · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Clay F. Semenkovich · 2013 to 2026
$27.1M
Institutional Training in the Genomic SciencesT32HG002760 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI Qiongshi Lu · 2003 to 2026
$17.7M
TR&D 2 Metabolic Labels for Ultraplexed Protein Quantification p. 453P41GM108538 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI COON, JOSHUA J · 2016 to 2025
$13.1M
Genetic Control of Metabolic Flux in Response to DietRC2DK125961 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI ATTIE, ALAN D · 2020 to 2024
$8.1M
The Diversity Outbred Diabetes ProjectR01DK101573 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Alan D Attie · 2014 to 2026
$5.3M
Regulation of Mitochondrial Metabolism by Post-Translational ModificationsR01DK098672 · NIDDK · WASHINGTON UNIVERSITY · PI David J Pagliarini · 2013 to 2026
$4.8M
The Role of Sorcs1 and Sortilin in Diabetes SusceptibilityR01DK102948 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI ATTIE, ALAN D · 2015 to 2019
$1.7M
NCI NIH HHS P30 CA014520NHGRI NIH HHS T32 HG002760NIDDK NIH HHS P30 DK020579NIDDK NIH HHS R01 DK098672NIDDK NIH HHS R01 DK101573NIDDK NIH HHS R01 DK102948NIDDK NIH HHS RC2 DK125961NIGMS NIH HHS P41 GM108538
6 · The paper itself

Abstract

Pptc7 is a resident mitochondrial phosphatase essential for maintaining proper mitochondrial content and function. Newborn mice lacking

Identifiers

PMID36909604
PMCPMC10002655
OpenAlexW4323038958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.